Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842167 | 0.86 | GPR84 (0.44) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL19475644 | 0.81 | FFAR1 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL19475641 | 0.81 | FFAR1 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL31626984 | 0.79 | GPR84 (0.50) | GPR84FFAR1MAPTLCKPPARD | |
| Choline SCHEMBL28707352 | 0.79 | PSMD14 (0.42) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL10420255 | 0.78 | FFAR1 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28707355 | 0.78 | GPR84 (0.41) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8818728 | 0.77 | GPR84 (0.47) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL2578866 | 0.75 | GPR84 (0.46) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28539179 | 0.75 | GPR84 (0.46) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9534008-B2 | Small molecule compounds that control plant- and insect-pathogenic nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-01-03 | — | — | US | disclosed |
| US-9487551-B2 | Small molecule compounds that control mammal-pathogenic nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-11-08 | — | — | US | disclosed |
| US-9445596-B2 | Small molecule compounds for the control of nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2016-09-20 | — | — | US | disclosed |
| US-20140364386-A1 | Small Molecule Compounds That Control Plant- and Insect-Pathogenic Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-12-11 | — | — | US | disclosed |
| US-20140303102-A1 | Small Molecule Compounds that Control Mammal-Pathogenic Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-10-09 | — | — | US | disclosed |
| US-20140303360-A1 | Small Molecule Compounds for the Control of Nematodes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303360-A1 | Small Molecule Compounds for the Control of Nematodes | MAVS, EMG1, PINK1 | GPR84 1268/4885FFAR1 3415/4885MAPT 4140/4885 |
| US-20140364386-A1 | Small Molecule Compounds That Control Plant- and Insect-Pathogenic Nematodes | HNMT, EMG1, API5 | GPR84 4338/4885FFAR1 4683/4885MAPT 2689/4885 |
| US-20140303102-A1 | Small Molecule Compounds that Control Mammal-Pathogenic Nematodes | EMG1, HNMT, MSN | GPR84 3577/4885FFAR1 4612/4885MAPT 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.