Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hypoxanthine SCHEMBL472854 | 0.86 | F7 (0.61) | ALDH1A1CYP3A4APPGAAHCAR3 | |
| Adenine SCHEMBL55284 | 0.83 | PI4KA (0.54) | ALDH1A1CYP3A4F7F3SARM1 | |
| Hypoxanthine SCHEMBL4083911 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP3A4APPGAAHCAR3 | |
| Adenine SCHEMBL6810324 | 0.80 | PI4KA (0.49) | ALDH1A1CYP3A4F7F3SARM1 | |
| Adenine SCHEMBL6480078 | 0.80 | PI4KA (0.49) | ALDH1A1CYP3A4F7F3SARM1 | |
| SCHEMBL29496911 | 0.78 | — | — | |
| SCHEMBL1699 | 0.78 | — | — | |
| SCHEMBL8039612 | 0.78 | — | — | |
| Hypoxanthine SCHEMBL9150757 | 0.78 | SIRT2 (0.50) | ALDH1A1CYP3A4APPGAAHCAR3 | |
| Iodide SCHEMBL10528928 | 0.77 | ALDH1A1 (0.63) | ALDH1A1CYP3A4APPGAAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385376-B1 | Triglyceride sensor | HOFFMANN LA ROCHE (CH) | 2016-10-05 | — | — | EP | disclosed |
| US-8187453-B2 | Triglyceride and cholesterol sensing method and sensor | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| EP-2385376-A1 | Triglyceride sensor | F. Hoffmann-La Roche AG (CH) | 2011-11-09 | — | — | EP | disclosed |
| US-20110086373-A1 | CHOLESTEROL SENSOR | ROCHE DIABETES CARE, INC. | 2011-04-14 | — | — | US | disclosed |
| EP-2121961-A2 | FORMULATION | Oxford Biosensors Limited (GB) | 2009-11-25 | — | — | EP | disclosed |
| US-20080268421-A1 | Cholesterol Sensor | ROCHE DIABETES CARE, INC. | 2008-10-30 | — | — | US | disclosed |
| EP-1963865-A2 | CHOLESTEROL SENSOR | Oxford Biosensors Limited (GB) | 2008-09-03 | — | — | EP | disclosed |
| WO-2008075072-A2 | FORMULATION | OXFORD BIOSENSORS LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |
| WO-2007072013-A2 | CHOLESTEROL SENSOR | OXFORD BIOSENSORS LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |
| US-20040121420-A1 | Method for detection of 4-hydroxybutyric acid and its precursor(s) in fluids | SMITH JACK V (US) | 2004-06-24 | — | — | US | disclosed |
| US-6617123-B1 | Contacting sample with mixture of an esterase, a pH indicator dye and a buffer; colorimetric analysis; easy, convenient test strips | SMITH JACK V (US) | 2003-09-09 | — | — | US | disclosed |
| EP-0158684-A1 | Hemoglobin-based blood gas control | Fisher Scientific Company (US) | 1985-10-23 | — | — | EP | disclosed |
| US-4485174-A | WITH BUFFER AND NUCLEOTIDE REDUCING AGENT | INSTRUMENTATION LABORATORY INC. (US) | 1984-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080268421-A1 | Cholesterol Sensor | HDLBP, CETP, APOB | ALDH1A1 4651/4885CYP3A4 2043/4885SLC2A1 1686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.