SCHEMBL1615060

SCHEMBL1615060

Cc1ccc(-c2cc(Br)cc(-c3ccc(C)cc3)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
MAPT P10636 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
ACHE P22303 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPK1 P28482 3/20 0.39
HTT P42858 1/20 0.39
ESR1 P03372 1/20 0.38
MAOB P27338 1/20 0.37
DHODH Q02127 1/20 0.37
MCL1 Q07820 1/20 0.36
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1047357 0.95 ALDH1A1 (0.52) ALDH1A1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL13072157 0.90 ALDH1A1 (0.68) ALDH1A1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL15678841 0.90 ALDH1A1 (0.68) ALDH1A1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL19288252 0.86 ACHE (0.57) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL4195128 0.86 ACHE (0.57) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL15036882 0.84 ALDH1A1 (0.42) ALDH1A1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL25951281 0.80 ACHE (0.50) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL260551 0.80 ALDH1A1 (0.81) ALDH1A1NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL18748288 0.80 ALDH1A1 (0.45) ALDH1A1NPC1RAB9AMAPTMEN1
SCHEMBL16218467 0.80 NPC1 (0.50) ALDH1A1NPC1RAB9AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12082493-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-09-03 US disclosed
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11690286-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-11690286-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-11690286-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-03 US disclosed
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-03 US disclosed
US-10957858-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-23 US disclosed
WO-2013070026-A1 1,1'-BINAPHTHYL-4,4'-DIAMINE DERIVATIVES FOR LUMINESCENCE OF ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THEM SAMYANGEMS CO., LTD. (KR) 2013-05-16 WO disclosed
EP-2511254-A2 Single triphenylene chromophores in phosphorescent light emitting diodes Universal Display Corporation (US) 2012-10-17 EP disclosed
EP-2511254-A2 Single triphenylene chromophores in phosphorescent light emitting diodes Universal Display Corporation (US) 2012-10-17 EP disclosed
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2011-04-14 US disclosed
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2011-04-14 US disclosed
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2011-04-14 US disclosed
EP-2200956-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2010-06-30 EP disclosed
US-20090146164-A1 Blue-Shifted Triarylamine Polymer CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2009-06-11 US disclosed
WO-2009021107-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed
WO-2009021107-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12082493-B2 Organic electroluminescent materials and devices NONO, ORC3, TYR ALDH1A1 668/4885NPC1 4073/4885RAB9A 771/4885
US-20110084599-A1 SINGLE TRIPHENYLENE CHROMOPHORES IN PHOSPHORESCENT LIGHT EMITTING DIODES TYR, PNP, MAPRE2 ALDH1A1 1731/4885NPC1 4543/4885RAB9A 1609/4885
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, TYR ALDH1A1 668/4885NPC1 4073/4885RAB9A 771/4885
US-10957858-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 ALDH1A1 320/4885NPC1 3804/4885RAB9A 764/4885
US-11690286-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 ALDH1A1 320/4885NPC1 3804/4885RAB9A 764/4885
US-20210167292-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, LEF1 ALDH1A1 320/4885NPC1 3804/4885RAB9A 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.