Malonic Acid

Malonic Acid

SCHEMBL1615262

CCN(CC)CC.CCN(CC)CC.CCN(CC)CC.O=C(O)CC(=O)O

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.56
SRR Q9GZT4 1/20 0.56
FFAR3 O14843 2/20 0.44
KDM5A P29375 2/20 0.38
KDM4C Q9H3R0 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
TSHR P16473 2/20 0.37
ALDH1A1 P00352 5/20 0.37
ALDH2 P05091 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
EYA2 O00167 1/20 0.36
APP P05067 1/20 0.36
ACE P12821 1/20 0.36
CHRM2 P08172 2/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL1615278 1.00 LDHA (0.56) LDHASRRFFAR3KDM5AKDM4C
Malonic Acid SCHEMBL217701 1.00 LDHA (0.56) LDHASRRFFAR3KDM5AKDM4C
Acetoacetic Acid SCHEMBL31393251 0.86 KDM4E (0.42) LDHASRRFFAR3KDM5AKDM4C
Propionic Acid SCHEMBL6546126 0.84 FFAR3 (0.67) FFAR3KDM5AKDM4CHDAC8HDAC3
Propionic Acid SCHEMBL3414192 0.84 FFAR3 (0.67) FFAR3KDM5AKDM4CHDAC8HDAC3
Bicarbonate SCHEMBL378701 0.83 FFAR3 (0.44) FFAR3HDAC8HDAC3HDAC1HDAC2
Bicarbonate SCHEMBL60768 0.83 FFAR3 (0.44) FFAR3HDAC8HDAC3HDAC1HDAC2
Succinic Acid SCHEMBL5874898 0.81 LMNA (0.56) FFAR3HDAC8HDAC3HDAC1HDAC2
Succinic Acid SCHEMBL217473 0.81 LMNA (0.56) FFAR3HDAC8HDAC3HDAC1HDAC2
Glycolic Acid SCHEMBL9721838 0.81 FFAR3 (0.44) FFAR3KDM5AKDM4CHDAC8HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2486453-B1 POSITIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING AZ ELECTRONIC MATERIALS USA (US) 2014-01-29 EP disclosed
EP-2486453-A1 POSITIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING AZ Electronic Materials USA Corp. (US) 2012-08-15 EP disclosed
CN-102576193-A Positive-working photoimageable bottom antireflective coating AZ ELECTRONIC MATERIALS USA 2012-07-11 CN disclosed
US-20110086312-A1 Positive-Working Photoimageable Bottom Antireflective Coating AZ ELECTRONIC MATERIALS USA CORP. 2011-04-14 US disclosed
WO-2011042770-A1 POSITIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING AZ ELECTRONIC MATERIALS USA CORP. (US) 2011-04-14 WO disclosed