Malonic Acid

Malonic Acid

SCHEMBL217701

CCN(CC)CC.O=C(O)CC(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.56
SRR Q9GZT4 1/20 0.56
FFAR3 O14843 2/20 0.44
KDM5A P29375 2/20 0.38
KDM4C Q9H3R0 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
TSHR P16473 2/20 0.37
ALDH1A1 P00352 5/20 0.37
ALDH2 P05091 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
EYA2 O00167 1/20 0.36
APP P05067 1/20 0.36
ACE P12821 1/20 0.36
CHRM2 P08172 2/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL1615278 1.00 LDHA (0.56) LDHASRRFFAR3KDM5AKDM4C
Malonic Acid SCHEMBL1615262 1.00 LDHA (0.56) LDHASRRFFAR3KDM5AKDM4C
Acetoacetic Acid SCHEMBL31393251 0.86 KDM4E (0.42) LDHASRRFFAR3KDM5AKDM4C
Propionic Acid SCHEMBL6546126 0.84 FFAR3 (0.67) FFAR3KDM5AKDM4CHDAC8HDAC3
Propionic Acid SCHEMBL3414192 0.84 FFAR3 (0.67) FFAR3KDM5AKDM4CHDAC8HDAC3
Bicarbonate SCHEMBL378701 0.83 FFAR3 (0.44) FFAR3HDAC8HDAC3HDAC1HDAC2
Bicarbonate SCHEMBL60768 0.83 FFAR3 (0.44) FFAR3HDAC8HDAC3HDAC1HDAC2
Succinic Acid SCHEMBL5874898 0.81 LMNA (0.56) FFAR3HDAC8HDAC3HDAC1HDAC2
Succinic Acid SCHEMBL217473 0.81 LMNA (0.56) FFAR3HDAC8HDAC3HDAC1HDAC2
Glycolic Acid SCHEMBL9721838 0.81 FFAR3 (0.44) FFAR3KDM5AKDM4CHDAC8HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2384457-B1 COATING COMPOSITIONS MERCK PATENT GMBH (DE) 2022-07-06 EP disclosed
CN-103597043-B Bottom antireflective coating compositions and its method 默克专利有限公司 2017-04-05 CN disclosed
CN-105694945-A Preparation method and application of protic ionic liquid 江苏大学 2016-06-22 CN disclosed
US-9146467-B2 Coating compositions MERCK PATENT GMBH (DE) 2015-09-29 US disclosed
CN-103869623-A Coating composition AZ ELECTRONIC MATERIALS USA 2014-06-18 CN disclosed
CN-102209937-B Coating composition AZ ELECTRONIC MATERIALS USA 2014-06-11 CN disclosed
CN-103597043-A Bottom antireflective coating compositions and processes thereof AZ ELECTRONIC MATERIALS USA 2014-02-19 CN disclosed
EP-2486453-B1 POSITIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING AZ ELECTRONIC MATERIALS USA (US) 2014-01-29 EP disclosed
US-20130236833-A1 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-09-12 US disclosed
US-8455176-B2 Coating composition AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-06-04 US disclosed
US-20110086312-A1 Positive-Working Photoimageable Bottom Antireflective Coating AZ ELECTRONIC MATERIALS USA CORP. 2011-04-14 US disclosed
CN-101264414-B Green high-efficiency recyclable SO2 gas absorbent and preparation thereof UNIV HEFEI TECHNOLOGY 2010-10-06 CN disclosed
EP-2212273-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2010-08-04 EP disclosed
WO-2010055406-A2 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-05-20 WO disclosed
US-20100119972-A1 COATING COMPOSITION MERCK PATENT GMBH (DE) 2010-05-13 US disclosed
WO-2009053832-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-30 WO disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 US disclosed
CN-101264414-A Green high-efficiency recyclable SO2 gas absorbent and preparation thereof UNIV HEFEI TECHNOLOGY (CN) 2008-09-17 CN disclosed
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 LDHA 3871/4885SRR 2619/4885FFAR3 1859/4885
US-20100119972-A1 COATING COMPOSITION S100A9, CAPG, C5 LDHA 4212/4885SRR 2920/4885FFAR3 2127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.