Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16156457 | 0.88 | LMNA (0.38) | NR1H2NR1H3MEN1ALDH1A1KMT2A | |
| SCHEMBL14690452 | 0.80 | NR1H2 (0.44) | NR1H2NR1H3MEN1ALDH1A1KMT2A | |
| SCHEMBL13527231 | 0.72 | GABRA1 (0.30) | CDK5CDK5R1 | |
| SCHEMBL10309299 | 0.70 | — | — | |
| SCHEMBL13002769 | 0.66 | GABRG2 (0.35) | CDK5CDK5R1 | |
| SCHEMBL16154007 | 0.66 | NR1H3 (0.48) | NR1H2NR1H3MEN1ALDH1A1KMT2A | |
| SCHEMBL16153981 | 0.64 | NR1H3 (0.48) | NR1H2NR1H3MEN1ALDH1A1KMT2A | |
| SCHEMBL16153980 | 0.63 | TDP2 (0.49) | NR1H2NR1H3MEN1ALDH1A1KMT2A | |
| SCHEMBL16153987 | 0.61 | NR1H3 (0.44) | NR1H2NR1H3MEN1ALDH1A1KMT2A | |
| SCHEMBL16153994 | 0.61 | NR1H3 (0.42) | NR1H2NR1H3MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198432-B2 | 1,2,4-triazolyl-substituted ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-20140302988-A1 | 1,2,4-Triazolyl-Substituted Ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140302988-A1 | 1,2,4-Triazolyl-Substituted Ketoenols | PIKFYVE, PHYKPL, KCNE1 | NR1H2 2368/4885NR1H3 1852/4885MEN1 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.