SCHEMBL1615677

SCHEMBL1615677

C=C(C)C(=O)OCC(CCCS(=O)(=O)O)N(C)C

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1616017 0.96 TSHR (0.42) TSHRTHRB
SCHEMBL1615291 0.91 TSHR (0.46) TSHRTHRBALDH1A1
SCHEMBL1616318 0.86 TSHR (0.41) TSHRTHRB
SCHEMBL1726114 0.80 TSHR (0.44) TSHRALDH1A1
SCHEMBL2237706 0.79 TSHR (0.54) TSHRTHRB
SCHEMBL13779875 0.79 TSHR (0.61) TSHRTHRBALDH1A1
SCHEMBL2161342 0.79 TSHR (0.52) TSHRTHRBALDH1A1
SCHEMBL11225874 0.79 TSHR (0.52) TSHRTHRBALDH1A1
SCHEMBL29089143 0.78 THRB (0.39) TSHRTHRB
SCHEMBL30377073 0.76 TSHR (0.49) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183515-A1 COATING COMPOSITION, USE AND METHODS FOR MAKING A SUBSTRATE FROST RESISTANT SOLVAY SA (BE) 2023-06-15 US claimed
EP-4136179-A1 COATING COMPOSITION, USE AND METHODS FOR MAKING A SUBSTRATE FROST RESISTANT Solvay SA (BE) 2023-02-22 EP claimed
CN-114080156-A Disinfectant composition 宝洁公司 2022-02-22 CN claimed
WO-2021208962-A1 Coating composition, use and methods for making a substrate frost resistant SOLVAY SA (BE) 2021-10-21 WO claimed
WO-2021160788-A1 METHODS FOR REDUCING OR PREVENTING COLLOIDS ADHESION AND/OR FOULING ON DIFFERENT SUBSTRATES, COMPOSITIONS, AND COPOLYMERS USEFUL THEREFOR SOLVAY SA (BE) 2021-08-19 WO claimed
WO-2021022290-A1 DISINFECTANT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2021-02-04 WO claimed
US-20210029999-A1 DISINFECTANT COMPOSITION THE PROCTER & GAMBLE COMPANY 2021-02-04 US claimed
EP-3771339-A1 DISINFECTANT COMPOSITION The Procter & Gamble Company (US) 2021-02-03 EP claimed
US-10815413-B2 Treatment of underground formations with gels RHODIA OPERATIONS (FR) 2020-10-27 US claimed
EP-2455441-B1 Oil field treatment fluids BAKER HUGHES A GE CO LLC (US) 2018-12-26 EP claimed
US-7956012-B2 Oil field treatment fluids with viscosified brines BJ SERVICES COMPANY LLC (US) 2011-06-07 US claimed
US-20100210724-A1 Method for modifying the properties of an aqueous suspension RHODIA OPERATIONS (FR) 2010-08-19 US claimed
WO-2010090738-A1 METHOD FOR MODIFYING THE PROPERTIES OF AN AQUEOUS SUSPENSION RHODIA OPERATIONS (FR) 2010-08-12 WO claimed
US-20100197530-A1 OIL FIELD TREATMENT FLUIDS WITH VISCOSIFIED BRINES BAKER HUGHES HOLDINGS LLC 2010-08-05 US claimed
US-20090197791-A1 COPOLYMER CONTAINING ZWITTERIONIC UNITS AND OTHER UNITS, COMPOSITION COMPRISING THE COPOLYMER, AND USE RHODIA RECHERCHES ET TECHNOLOGIES (FR) 2009-08-06 US claimed
US-20080045420-A1 Zwitterionic Polymers Comprising Betaine-Type Units And Use Of Zwitterionic Polymers In Drilling Fluids RHODIA CHIMIE (FR) 2008-02-21 US claimed
US-20060217286-A1 Composition for cleaning or rinsing hard surfaces SPECIALTY OPERATIONS FRANCE (FR) 2006-09-28 US claimed
EP-0563299-A4 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM CESKOSLOVENSKA AKADEMIE VED (CS) 1994-07-20 EP claimed
EP-0563299-A1 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM Hydron Limited (GB) 1993-10-06 EP claimed
WO-1992011301-A1 BALANCED CHARGE POLYMER AND HYDROPHILIC CONTACT LENS MANUFACTURED THEREFROM ALLERGAN, INC. (US) 1992-07-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210724-A1 Method for modifying the properties of an aqueous suspension APOB, HBB, SLC6A12 TSHR 4176/4885THRB 1770/4885ALDH1A1 2785/4885
US-20210029999-A1 DISINFECTANT COMPOSITION ALKBH1, ALKBH5, POLL TSHR 3911/4885THRB 3188/4885ALDH1A1 1296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.