SCHEMBL16162256

SCHEMBL16162256

CN(C)c1ccc(B(O)OC(C)(C)C(C)(C)O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.41
ALDH1A1 P00352 9/20 0.38
TSHR P16473 4/20 0.38
ALOX15 P16050 4/20 0.38
HSD17B10 Q99714 2/20 0.38
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
CYP3A4 P08684 3/20 0.32
MAPK1 P28482 3/20 0.32
TDP1 Q9NUW8 3/20 0.32
HBB P68871 1/20 0.32
TP53 P04637 1/20 0.32
APP P05067 3/20 0.32
PTGS1 P23219 1/20 0.32
GAA P10253 3/20 0.32
KDM4E B2RXH2 2/20 0.32
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14645520 0.82 CA2 (0.41) ALDH1A1TSHR
SCHEMBL15391292 0.82 ALDH1A1 (0.35) ALDH1A1MAPTCYP3A4TDP1KDM4E
SCHEMBL19433226 0.82 CA2 (0.42) TSHR
SCHEMBL22684756 0.81 ALDH1A1 (0.40) SLC2A1ALDH1A1TSHRHSD17B10APP
SCHEMBL1181137 0.80 ENPP2 (0.41) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL3681691 0.80 CA2 (0.45) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL4260818 0.80 TTR (0.38) APPPTGS1
SCHEMBL3393899 0.79 HRH3 (0.40) ALDH1A1TSHRGAANOS1
SCHEMBL3711217 0.79
SCHEMBL117688 0.79 ENPP2 (0.43) TSHRMAPTCYP3A4MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 US disclosed
WO-2024262927-A1 NOVEL FLUORESCENT COMPOUND, AND COMPOSITION FOR DETECTING GINGIPAIN, COMPOSITION FOR DIAGNOSING PORPHYROMONAS GINGIVALIS INFECTION, OR ANTIBACTERIAL COMPOSITION AGAINST PORPHYROMONAS GINGIVALIS USING SAME 한국과학기술연구원 2024-12-26 WO disclosed
US-20220396553-A1 NOVEL HYDRAZONE DERIVATIVE IN WHICH TERMINAL AMINE GROUP IS SUBSTITUTED WITH ARYL GROUP OR HETEROARYL GROUP, AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2022-12-15 US disclosed
EP-3901139-A1 NOVEL HYDRAZONE DERIVATIVE WITH ARYL OR HETEROARYL GROUP SUBSTITUTED AT TERMINAL AMINE GROUP THEREOF AND USE THEREOF Korea Institute of Science and Technology (KR) 2021-10-27 EP disclosed
WO-2020130214-A1 NOVEL HYDRAZONE DERIVATIVE WITH ARYL OR HETEROARYL GROUP SUBSTITUTED AT TERMINAL AMINE GROUP THEREOF AND USE THEREOF 한국과학기술연구원 2020-06-25 WO disclosed
US-9480166-B2 Method of manufacturing non-firing type electrode E I DU PONT DE NEMOURS AND COMPANY (US) 2016-10-25 US disclosed
EP-2986666-A1 METHOD OF MANUFACTURING NON-FIRED TYPE ELECTRODE E. I. du Pont de Nemours and Company (US) 2016-02-24 EP disclosed
WO-2014172137-A1 METHOD OF MANUFACTURING NON-FIRED TYPE ELECTRODE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-10-23 WO disclosed
US-20140306165-A1 METHOD OF MANUFACTURING NON-FIRING TYPE ELECTRODE E I DU PONT DE NEMOURS AND COMPANY (US) 2014-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof ABL1, TH, CYP3A43 SLC2A1 2075/4885ALDH1A1 1008/4885TSHR 1191/4885
US-20220396553-A1 NOVEL HYDRAZONE DERIVATIVE IN WHICH TERMINAL AMINE GROUP IS SUBSTITUTED WITH ARYL GROUP OR HETEROARYL GROUP, AND USE THEREOF AANAT, NAT1, HNMT SLC2A1 3906/4885ALDH1A1 402/4885TSHR 776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.