Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 9/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676255 | 0.81 | ACHE (0.43) | MMP2MMP9MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL12893245 | 0.78 | ALDH1A1 (0.51) | MMP2MMP9MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL29356095 | 0.72 | ACHE (0.49) | ALDH1A1LMNAACHEBCHECHRM2 | |
| SCHEMBL461129 | 0.72 | ACHE (0.49) | ALDH1A1LMNAACHEBCHECHRM2 | |
| SCHEMBL2182880 | 0.71 | LMNA (0.59) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL9326191 | 0.71 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL27513052 | 0.71 | KDM4E (0.53) | MMP2MMP9MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL188010 | 0.70 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL2540440 | 0.70 | ALDH1A1 (0.45) | MMP2MMP9MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL11599136 | 0.70 | ALDH1A1 (0.45) | MMP2MMP9MMP14ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947371-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | Syngenta Crop Protection AG (CH) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020193618-A1 | MICROBIOCIDAL THIAZOLE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2020-10-01 | — | — | WO | disclosed |
| EP-3649118-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019008072-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-10 | — | — | WO | disclosed |
| WO-2018153778-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-30 | — | — | WO | disclosed |
| EP-2984083-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | Syngenta Participations AG (CH) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014166795-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-16 | — | — | WO | disclosed |