Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.43 |
| ▸ | BCHE | P06276 | 6/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089269 | 0.82 | ACHE (0.46) | ACHEBCHESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11097182 | 0.81 | LMNA (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL16166141 | 0.81 | MMP2 (0.39) | ACHEBCHEMMP2MMP9MMP14 | |
| SCHEMBL12893245 | 0.78 | ALDH1A1 (0.51) | ACHEBCHEMMP2MMP9MMP14 | |
| SCHEMBL9063871 | 0.76 | KMT2A (0.52) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL6733945 | 0.72 | ACHE (0.49) | ACHEBCHEALDH1A1LMNA | |
| SCHEMBL119641 | 0.72 | ACHE (0.49) | ACHEBCHEALDH1A1LMNA | |
| SCHEMBL29435143 | 0.72 | ACHE (0.49) | ACHEBCHEALDH1A1LMNA | |
| SCHEMBL2360322 | 0.71 | NPC1 (0.71) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL4723773 | 0.71 | MAOA (0.48) | ACHESMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846997-A | Liquid formulations | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |