Sugi Predict

Sugi Predict / Compounds / SCHEMBL16166310

SCHEMBL16166310

SCHEMBL16166310

CCC(C)C(=S)N(CC)c1sc(-c2cccnc2)nc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ USP2 O75604 1/20 0.38
▸ KDM4E B2RXH2 5/20 0.38
▸ ALOX5 P09917 1/20 0.38
▸ CYP1A2 P05177 3/20 0.37
▸ CYP3A4 P08684 3/20 0.37
▸ CYP2C19 P33261 2/20 0.37
▸ LMNA P02545 1/20 0.37
▸ S1PR1 P21453 3/20 0.37
▸ TRPM8 Q7Z2W7 1/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ CYP2D6 P10635 1/20 0.36
▸ CYP2C9 P11712 1/20 0.36
▸ KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29597024 1.00 NPC1 (0.39) NPC1RAB9AHSD17B10ALDH1A1MAPK1
SCHEMBL13048879 0.88 NPC1 (0.42) NPC1RAB9AHSD17B10ALDH1A1MAPK1
SCHEMBL29595613 0.88 CYP3A4 (0.46) NPC1RAB9AHSD17B10ALDH1A1MAPK1
SCHEMBL16166594 0.88 CYP3A4 (0.46) NPC1RAB9AHSD17B10ALDH1A1MAPK1
SCHEMBL29595760 0.88 ALOX5 (0.38) NPC1RAB9AHSD17B10ALDH1A1KDM4E
SCHEMBL16166055 0.88 ALOX5 (0.38) NPC1RAB9AHSD17B10ALDH1A1KDM4E
SCHEMBL29596499 0.83 S1PR1 (0.40) NPC1RAB9AHSD17B10ALDH1A1MAPK1
SCHEMBL13048229 0.83 NPC1 (0.44) NPC1RAB9AHSD17B10ALDH1A1MAPK1
SCHEMBL16166062 0.83 S1PR1 (0.40) NPC1RAB9AHSD17B10ALDH1A1MAPK1
SCHEMBL23726147 0.83 HSD17B10 (0.48) NPC1RAB9AHSD17B10ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2024-07-11 — — US claimed
EP-4346412-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI Industries Ltd. (IN) 2024-04-10 — — EP claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 — — US claimed
EP-3978504-A1 CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2022-04-06 — — EP claimed
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF BASF SE (DE) 2022-02-17 — — US claimed
EP-3601298-B1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-12-01 — — EP claimed
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests BASF SE (DE) 2021-11-18 — — US claimed
CN-113367135-A Agricultural mixtures comprising carboxamide compounds 巴斯夫农业化学品有限公司 2021-09-10 — — CN claimed
CN-113303339-A Mixture of cis-jasmone and bacillus amyloliquefaciens 巴斯夫欧洲公司 2021-08-27 — — CN claimed
EP-3057419-B1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF AGROCHEMICAL PRODUCTS BV (NL) 2021-07-28 — — EP claimed
EP-3057418-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products, B.V. (NL) 2016-08-24 — — EP claimed
EP-3057420-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF Agrochemical Products B.V. (NL) 2016-08-24 — — EP claimed
EP-3057419-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products B.V. (NL) 2016-08-24 — — EP claimed
WO-2016128261-A2 PESTICIDAL MIXTURE COMPRISING A PYRAZOLE COMPOUND, AN INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2016-08-18 — — WO claimed
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 — — US claimed
WO-2016059240-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2016-04-21 — — WO claimed
WO-2015055755-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055757-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF SE (DE) 2015-04-23 — — WO claimed
WO-2015055752-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH NPC1 3390/4885RAB9A 3415/4885HSD17B10 1723/4885
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND NAAA, AADAC, PYCARD NPC1 3048/4885RAB9A 2911/4885HSD17B10 4280/4885
US-20160227771-A1 Insecticidal Active Mixtures Comprising Carboxamide Compound ATP5ME, MT-ATP6, ATP5MG NPC1 1903/4885RAB9A 3763/4885HSD17B10 2044/4885
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS OXA1L, NOX1, NOX3 NPC1 2904/4885RAB9A 2630/4885HSD17B10 563/4885
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF MANBA, CMA1, MTX1 NPC1 2502/4885RAB9A 882/4885HSD17B10 1200/4885
US-20210355139-A1 Pyrimidinium Compounds and Their Mixtures for Combating Animal Pests THOP1, NIT2, DDT NPC1 2964/4885RAB9A 1802/4885HSD17B10 3915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.