SCHEMBL1616641

SCHEMBL1616641

O=C(Cl)c1ccc(O)c(O)c1O

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.62
SELP P16109 1/20 0.62
HDAC1 Q13547 1/20 0.52
PIK3CA P42336 5/20 0.50
TERT O14746 1/20 0.43
ALDH1A1 P00352 3/20 0.41
ALOX15 P16050 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
HPGD P15428 2/20 0.41
RECQL P46063 1/20 0.41
HSD17B10 Q99714 1/20 0.41
POLB P06746 1/20 0.38
RAB9A P51151 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30863510 1.00 SELL (0.62) SELLSELPHDAC1PIK3CATERT
SCHEMBL5298121 0.89 SELL (0.46) SELLSELPHDAC1PIK3CAALDH1A1
SCHEMBL1435291 0.83 ALDH1A1 (0.50) SELLSELPTERTALDH1A1ALOX15
SCHEMBL28842145 0.83 SELL (0.48) SELLSELPHDAC1PIK3CAALDH1A1
SCHEMBL9492963 0.81 SELL (0.41) SELLSELPHDAC1PIK3CAALDH1A1
SCHEMBL8345529 0.81 SELL (0.41) SELLSELPHDAC1PIK3CAALDH1A1
SCHEMBL1063407 0.79 SELL (0.68) SELLSELPHDAC1PIK3CATERT
SCHEMBL28135908 0.78 DPP4 (0.46) SELLSELPPIK3CAALDH1A1ALOX15
SCHEMBL6858983 0.77 SELL (0.65) SELLSELPHDAC1PIK3CATERT
SCHEMBL31236653 0.77 SELL (1.00) SELLSELPHDAC1PIK3CAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850225-B Application of hesperidin and method for semisynthesis preparation of chrysin by using hesperidin derivative 三原润禾生物科技有限公司 2024-06-28 CN disclosed
US-7923587-B2 Anti-oxidant macromonomers and polymers and methods of making and using the same POLNOX CORPORATION (US) 2011-04-12 US disclosed
EP-1771530-B1 ANTI-OXIDANT MACROMONOMERS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME POLNOX CORP (US) 2009-09-09 EP disclosed
US-20080311065-A1 Anti-oxidant macromonomers and polymers and methods of making and using the same POLNOX CORPORATION 2008-12-18 US disclosed
EP-1214070-A4 POLYHYDROXYLATED BENZENE-CONTAINING COMPOUNDS ARCH DEV CORP (US) 2008-07-16 EP disclosed
EP-1776394-A2 ANTI-OXIDANT MACROMONOMERS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME Polnox Corporation (US) 2007-04-25 EP disclosed
EP-1771530-A2 ANTI-OXIDANT MACROMONOMERS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME Polnox Corporation (US) 2007-04-11 EP disclosed
US-20060041087-A1 Anti-oxidant macromonomers and polymers and methods of making and using the same POLNOX CORPORATION 2006-02-23 US disclosed
US-20060041094-A1 Anti-oxidant macromonomers and polymers and methods of making and using the same POLNOX CORPORATION 2006-02-23 US disclosed
WO-2006014674-A2 ANTI-OXIDANT MACROMONOMERS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION (US) 2006-02-09 WO disclosed
WO-2006014605-A2 ANTI-OXIDANT MACROMONOMERS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION (US) 2006-02-09 WO disclosed
US-20050113426-A1 Polyhydroxylated benzene-containing compounds NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-05-26 US disclosed
US-6610749-B2 A method for reducing food intake in a subject and a method for reducing the levels of an endocrine in a subject ARCH DEVELOPMENT CORPORATION 2003-08-26 US disclosed
US-20030139477-A1 Polyhydroxylated benzene-containing compounds NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-07-24 US disclosed
EP-1214070-A2 POLYHYDROXYLATED BENZENE-CONTAINING COMPOUNDS Arch Development Corporation (US) 2002-06-19 EP disclosed
WO-2001060319-A2 POLYHYDROXYLATED BENZENE-CONTAINING COMPOUNDS ARCH DEVELOPMENT CORPORATION (US) 2001-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311065-A1 Anti-oxidant macromonomers and polymers and methods of making and using the same GPX4, LPO, GPX1 SELL 605/4885SELP 411/4885HDAC1 2567/4885
US-20050113426-A1 Polyhydroxylated benzene-containing compounds LIPE, PNLIP, LIPA SELL 3047/4885SELP 3677/4885HDAC1 2063/4885
US-20030139477-A1 Polyhydroxylated benzene-containing compounds LIPE, PNLIP, SHBG SELL 3307/4885SELP 3850/4885HDAC1 1745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.