Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.46 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.46 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.46 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.46 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16169687 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C9CYP2C19CYP1A2CYP19A1 | |
| SCHEMBL16419742 | 0.92 | LTA4H (0.49) | SMN1; SMN2CYP2C9CYP2C19CYP1A2CYP19A1 | |
| SCHEMBL15805902 | 0.92 | CYP1A1 (0.48) | SMN1; SMN2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL16419782 | 0.92 | CYP1A1 (0.48) | SMN1; SMN2CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL16169683 | 0.90 | PLA2G2A (0.43) | SMN1; SMN2CYP2C9CYP2C19CYP1A2CYP19A1 | |
| SCHEMBL16169673 | 0.85 | NOS3 (0.42) | SMN1; SMN2CYP2C9CYP2C19CYP1A2CYP19A1 | |
| SCHEMBL16169670 | 0.85 | CYP1A2 (0.38) | SMN1; SMN2CYP2C9CYP2C19CYP1A2CYP19A1 | |
| SCHEMBL16419743 | 0.84 | CHRNB2 (0.43) | SMN1; SMN2CYP2C9CYP2C19CYP1A2CYP19A1 | |
| SCHEMBL16419735 | 0.84 | CYP2D6 (0.45) | CYP2C9CYP2C19CYP1A2CYP19A1CYP3A4 | |
| SCHEMBL18020389 | 0.84 | PLA2G2A (0.47) | CYP2C9CYP2C19CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469616-B2 | Cyclic compounds and methods of making and using the same | CELLCEUTIX CORPORATION (US) | 2016-10-18 | — | — | US | disclosed |
| US-20150031738-A1 | CYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | UNIVERSITY OF MASSACHUSETTS (US) | 2015-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031738-A1 | CYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MUC1, TLR3, ALG1 | SMN1; SMN2 4729/4885CYP2C9 3711/4885CYP2C19 3400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.