SCHEMBL16176132

SCHEMBL16176132

CC1(C)c2ccccc2-c2ccc3c(c21)c1ccccc1n3-c1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ PGR P06401 2/20 0.32
▸ MAPK14 Q16539 1/20 0.30
▸ PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17245791 0.94 KDM4E (0.35) KDM4EATML3MBTL1PGRMAPK14
SCHEMBL17989580 0.93 KDM4E (0.30) KDM4EATML3MBTL1
SCHEMBL17989585 0.92 KDM4E (0.31) KDM4EATML3MBTL1
SCHEMBL24125495 0.91 RXFP1 (0.30) —
SCHEMBL10014095 0.91 L3MBTL1 (0.37) KDM4EATML3MBTL1PGRMAPK14
SCHEMBL24230606 0.90 KDM4E (0.31) KDM4EATML3MBTL1
SCHEMBL16283073 0.88 KDM4E (0.38) KDM4EATML3MBTL1PGRPDK2
SCHEMBL10014072 0.88 KDM4E (0.45) KDM4EATML3MBTL1PGR
SCHEMBL802613 0.88 FLT3 (0.33) KDM4EATML3MBTL1PGRPDK2
SCHEMBL17989622 0.88 KDM4E (0.31) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 — — US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 — — US disclosed
US-20230329081-A1 Light Emitting Device and Composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-12 — — US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 — — US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 — — US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 — — US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 — — US disclosed
EP-3752512-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-03-01 — — EP disclosed
EP-3005433-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2023-02-22 — — EP disclosed
US-11569458-B2 Metal complexes MERCK PATENT GMBH (DE) 2023-01-31 — — US disclosed
WO-2018069196-A1 BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES MERCK PATENT GMBH (DE) 2018-04-19 — — WO disclosed
WO-2018069273-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2018-04-19 — — WO disclosed
WO-2018069197-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2018-04-19 — — WO disclosed
WO-2018054798-A1 BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-03-29 — — WO disclosed
WO-2018041769-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-03-08 — — WO disclosed
US-20170077418-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2017-03-16 — — US disclosed
US-20170077418-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2017-03-16 — — US disclosed
US-20160093813-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2016-03-31 — — US disclosed
US-20160093813-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2016-03-31 — — US disclosed
WO-2014166585-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-10-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170077418-A1 ORGANIC ELECTROLUMINESCENT DEVICE EPCAM, L1CAM, LAGE3 KDM4E 2425/4885ATM 2599/4885L3MBTL1 107/4885
US-20230320191-A1 METAL COMPLEXES IMMT, MCU, SOD1 KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885
US-11659763-B2 Metal complexes IMMT, MCU, SOD1 KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885
US-11569458-B2 Metal complexes IMMT, MCU, SOD1 KDM4E 4470/4885ATM 4048/4885L3MBTL1 3259/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 KDM4E 3870/4885ATM 3416/4885L3MBTL1 2532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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