Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.73 |
| ▸ | MMP9 | P14780 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.66 |
| ▸ | UQCRB | P14927 | 1/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260612 | 0.83 | HKDC1 (0.66) | ALDH1A1GAAGFERSMN1; SMN2MEN1 | |
| SCHEMBL16187967 | 0.83 | MMP2 (1.00) | MMP2MMP9TDP1KDM4ENPC1 | |
| SCHEMBL26241643 | 0.81 | TDP1 (0.97) | MMP2MMP9TDP1KDM4ENPC1 | |
| SCHEMBL6979087 | 0.80 | TDP1 (1.00) | TDP1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL17962342 | 0.79 | COMT (0.67) | MMP2TDP1KDM4EMEN1KMT2A | |
| SCHEMBL16187968 | 0.79 | UQCRB (1.00) | MMP2MMP9TDP1KDM4ENPC1 | |
| SCHEMBL22076981 | 0.78 | MEN1 (1.00) | TDP1HTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL416258 | 0.76 | MEN1 (0.73) | TDP1SMN1; SMN2MEN1KMT2AGLO1 | |
| SCHEMBL13509965 | 0.76 | MEN1 (0.83) | MMP2TDP1KDM4EALDH1A1GAA | |
| SCHEMBL3260752 | 0.75 | MEN1 (0.62) | TDP1ALDH1A1GAAHTTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |
| US-9371286-B2 | Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2016-06-21 | — | — | US | disclosed |
| US-20140315947-A1 | PHARMACEUTICAL COMPOSITION WITH ENHANCED EFFICACY FOR INHIBITING ANGIOGENESIS | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2014-10-23 | — | — | US | disclosed |
| US-20140315947-A1 | PHARMACEUTICAL COMPOSITION WITH ENHANCED EFFICACY FOR INHIBITING ANGIOGENESIS | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315947-A1 | PHARMACEUTICAL COMPOSITION WITH ENHANCED EFFICACY FOR INHIBITING ANGIOGENESIS | UQCRB, UQCRC1, UQCRC2 | MMP2 2721/4885MMP9 3879/4885TDP1 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.