Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783976 | 0.81 | RAB9A (0.46) | LTA4HALDH1A1HTR2ANPC1RAB9A | |
| SCHEMBL4324165 | 0.81 | LTA4H (0.37) | LTA4HALDH1A1HTTNPSR1HTR1A | |
| SCHEMBL3950203 | 0.80 | LMNA (0.35) | ALDH1A1PIK3CDNPC1RAB9AMEN1 | |
| SCHEMBL21051920 | 0.79 | LTA4H (0.39) | LTA4HALDH1A1HTTNPSR1HTR1A | |
| SCHEMBL24310851 | 0.78 | KDM4E (0.52) | ALDH1A1POLBPKMTSHRGAA | |
| SCHEMBL1754059 | 0.78 | PIK3CD (0.53) | ALDH1A1PIK3CDMEN1USP2KMT2A | |
| SCHEMBL28374092 | 0.78 | — | — | |
| SCHEMBL422638 | 0.75 | — | — | |
| SCHEMBL572569 | 0.75 | ALDH1A1 (0.45) | LTA4HALDH1A1HTTNPSR1HTR1A | |
| SCHEMBL7917431 | 0.75 | LTA4H (0.37) | LTA4HALDH1A1HTTNPSR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014169836-A1 | 19-NOR NEUROACTIVE STEROIDS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. (US) | 2014-10-23 | — | — | WO | disclosed |