Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572569 | 0.81 | ALDH1A1 (0.45) | LTA4HALDH1A1HTTNPSR1HTR1A | |
| SCHEMBL422638 | 0.81 | — | — | |
| SCHEMBL12862298 | 0.78 | PIK3CD (0.57) | ALDH1A1NPSR1PIK3CDKDM4EL3MBTL1 | |
| SCHEMBL1115936 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1KDM4E | |
| SCHEMBL14392151 | 0.78 | KEAP1 (0.47) | LTA4HALOX15SIGMAR1 | |
| SCHEMBL24803014 | 0.76 | GAA (0.40) | ALDH1A1TSHRGAAKDM4EL3MBTL1 | |
| SCHEMBL2847464 | 0.76 | HSD11B1 (0.49) | LTA4HALDH1A1HTTTSHRPOLB | |
| SCHEMBL10826454 | 0.76 | HSD17B10 (0.48) | LTA4HALDH1A1TSHRPOLBPKM | |
| SCHEMBL31416857 | 0.76 | SIGMAR1 (0.44) | LTA4HHTR1AHTR7ALOX15SIGMAR1 | |
| SCHEMBL20038482 | 0.75 | KDM4E (0.58) | ALDH1A1TSHRPOLBPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214604-B1 | PURE CULTURE OF BURKHOLDERIA STRAIN DSM 9925 | LONZA AG (CH) | 2001-04-10 | — | — | US | claimed |
| US-6214604-B1 | PURE CULTURE OF BURKHOLDERIA STRAIN DSM 9925 | LONZA AG (CH) | 2001-04-10 | — | — | US | disclosed |