Sugi Predict

Sugi Predict / Compounds / SCHEMBL161900

SCHEMBL161900

SCHEMBL161900

O=C(Cl)c1ccc(S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 2/20 0.58
▸ HPGD P15428 3/20 0.56
▸ KMT2A Q03164 2/20 0.56
▸ MEN1 O00255 1/20 0.56
▸ LMNA P02545 3/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ MAPT P10636 2/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ GAA P10253 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51
▸ NAMPT P43490 2/20 0.50
▸ PRMT1 Q99873 2/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL724893 0.91 ALDH1A1 (0.50) HTR6HPGDKMT2AMEN1LMNA
SCHEMBL725823 0.85 KMT2A (0.46) HTR6HPGDKMT2AMEN1LMNA
(Phenylsulfonyl)Benzene SCHEMBL29100684 0.84 HTR6 (0.54) HTR6HPGDKMT2AMEN1LMNA
SCHEMBL165237 0.83 HTR6 (0.64) HTR6HPGDKMT2AMEN1LMNA
SCHEMBL12123514 0.82 MAPT (0.53) HPGDKMT2ALMNAMAPTALDH1A1
SCHEMBL14387536 0.82 ALDH1A1 (0.42) HTR6HPGDKMT2AMEN1LMNA
SCHEMBL7311605 0.82 GAA (0.64) HPGDKMT2AMEN1LMNAMAPT
SCHEMBL11594739 0.81 CES2 (0.65) HTR6HPGDKMT2AMEN1LMNA
SCHEMBL9769557 0.80 POLB (0.55) HPGDKMT2AMEN1LMNAL3MBTL1
(Phenylsulfonyl)Benzene SCHEMBL7774155 0.79 HTR6 (0.82) HTR6HPGDKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118703088-B Ageing-resistant acrylic resin waterproof paint 内蒙古安特威盾防水科技有限公司 2024-11-19 — — CN claimed
CN-118703088-A Ageing-resistant acrylic resin waterproof paint 内蒙古安特威盾防水科技有限公司 2024-09-27 — — CN claimed
CN-118703088-B Ageing-resistant acrylic resin waterproof paint 内蒙古安特威盾防水科技有限公司 2024-11-19 — — CN disclosed
CN-118703088-A Ageing-resistant acrylic resin waterproof paint 内蒙古安特威盾防水科技有限公司 2024-09-27 — — CN disclosed
US-11773068-B2 KDM1A inhibitors for the treatment of disease IMAGO BIOSCIENCES, INC. (US) 2023-10-03 — — US disclosed
US-11279687-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2022-03-22 — — US disclosed
US-11230534-B2 KDM1A inhibitors for the treatment of disease IMAGO BIOSCIENCES, INC. (US) 2022-01-25 — — US disclosed
US-20200283397-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE IMAGO BIOSCIENCES, INC. 2020-09-10 — — US disclosed
US-20200283403-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT Valo Health, LLC 2020-09-10 — — US disclosed
US-10647695-B2 Compounds and compositions for the inhibition of NAMPT FORMA TM, LLC (US) 2020-05-12 — — US disclosed
US-20190270721-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT Valo Health, LLC 2019-09-05 — — US disclosed
US-5428161-A Having at least one electron-withdrawing substituent on at least one of the groups attached to the amine groups at the 3- and 7-positions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-06-27 — — US disclosed
EP-0244399-B1 NOVEL PHENAZINE DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-30 — — EP disclosed
US-4889932-A THERMOGRAPHY; COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-12-26 — — US disclosed
EP-0339869-A2 Novel phenazine dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-11-02 — — EP disclosed
EP-0181085-B1 STABILIZED LEUCO PHENAZINE DYES AND THEIR USE IN AN IMAGING SYSTEM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-08-09 — — EP disclosed
EP-0244399-A1 NOVEL PHENAZINE DYES. MINNESOTA MINING & MFG (US) 1987-11-11 — — EP disclosed
WO-1987002048-A1 NOVEL PHENAZINE DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-04-09 — — WO disclosed
US-4647525-A Stabilized leuco phenazine dyes and their use in an imaging system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-03-03 — — US disclosed
EP-0181085-A1 Stabilized leuco phenazine dyes and their use in an imaging system MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-05-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647695-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNT, NQO1 HTR6 1044/4885HPGD 199/4885KMT2A 659/4885
US-20200283403-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT NAMPT, HAMP, NQO1 HTR6 1196/4885HPGD 335/4885KMT2A 1299/4885
US-11279687-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNT, NQO1 HTR6 1044/4885HPGD 199/4885KMT2A 659/4885
US-20200283397-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE KDM1B, KDM1A, KDM2A HTR6 3374/4885HPGD 1669/4885KMT2A 14/4885
US-11230534-B2 KDM1A inhibitors for the treatment of disease KDM1B, KDM1A, KDM2A HTR6 3374/4885HPGD 1669/4885KMT2A 14/4885
US-11773068-B2 KDM1A inhibitors for the treatment of disease KDM1B, KDM1A, KDM2A HTR6 3374/4885HPGD 1669/4885KMT2A 14/4885
US-20190270721-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT NAMPT, HAMP, NQO1 HTR6 1196/4885HPGD 335/4885KMT2A 1299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.