Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 7/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16191961 | 1.00 | NQO2 (0.61) | NQO2PTGS1MEN1KMT2ATP53 | |
| SCHEMBL919577 | 0.80 | ALDH1A1 (0.55) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL16960424 | 0.80 | TTR (0.54) | NQO2PTGS1MEN1KMT2ATP53 | |
| SCHEMBL16954598 | 0.79 | KMT2A (0.48) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL16191734 | 0.78 | PTGS1 (0.70) | NQO2PTGS1MEN1KMT2AKDM4E | |
| SCHEMBL16951781 | 0.78 | KDM4E (0.53) | NQO2PTGS1MEN1KMT2ATP53 | |
| SCHEMBL16191732 | 0.78 | PTGS1 (0.70) | NQO2PTGS1MEN1KMT2AKDM4E | |
| SCHEMBL16290846 | 0.78 | PDE4A (0.54) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL20836735 | 0.78 | PDE4A (0.54) | MEN1KMT2ATP53SMN1; SMN2KDM4E | |
| SCHEMBL13725392 | 0.78 | RXRA (0.53) | MEN1KMT2ATP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2796442-B1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INST MED BIOTECHNOLOGY CAMS (CN) | 2019-03-27 | — | — | EP | disclosed |
| US-9359298-B2 | Cajanine structure analogous compound, preparation method and use | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-06-07 | — | — | US | disclosed |
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2014-12-18 | — | — | US | disclosed |
| EP-2796442-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2014-10-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371232-A1 | CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE | ACHE, GAP43, LNPK | NQO2 4644/4885PTGS1 2474/4885MEN1 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.