SCHEMBL16201985

SCHEMBL16201985

Cc1ccn(-c2ccc(F)c(C)c2)n1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 4/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 2/20 0.44
RAB9A P51151 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
KCNH2 Q12809 2/20 0.44
NPC1 O15118 1/20 0.42
ATM Q13315 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
RXRA P19793 10/20 0.41
GRIN1 Q05586 10/20 0.41
GRIN2B Q13224 10/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15984869 0.83 HTT (0.50) KAT6AHTTMAPTRAB9AKDM4E
SCHEMBL15056697 0.83 RAB9A (0.54) KAT6AHTTMAPTRAB9AKDM4E
SCHEMBL16201986 0.83 KCNH2 (0.46) KAT6AHTTMAPTRAB9AKDM4E
SCHEMBL15056904 0.83 RXRA (0.45) KAT6AHTTMAPTRAB9AKDM4E
SCHEMBL16911624 0.79 RAB9A (0.54) KAT6AHTTMAPTRAB9AKDM4E
SCHEMBL3833826 0.79 HTT (0.47) KAT6AHTTMAPTRAB9AKDM4E
SCHEMBL16202096 0.79 KCNH2 (0.46) KAT6AHTTMAPTRAB9AKDM4E
SCHEMBL16911268 0.79 RAB9A (0.58) KAT6AHTTMAPTRAB9AKDM4E
SCHEMBL16202105 0.78 RAB9A (0.47) KAT6AHTTMAPTRAB9AKDM4E
SCHEMBL20462877 0.78 KAT6A (0.61) KAT6AHTTMAPTRAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2016-09-01 US disclosed
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-26 US disclosed
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi BASF SE (DE) 2016-05-26 US disclosed
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-05 US disclosed
US-9271501-B2 Use of strobilurin type compounds for combating phytopathogenic fungi resistant to QO inhibitors BASF SE (DE) 2016-03-01 US disclosed
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2014-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI SNX1, DPM1, SNU13 KAT6A 4678/4885HTT 3148/4885MAPT 1798/4885
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI DPM1, CROCC, SNX1 KAT6A 4479/4885HTT 2598/4885MAPT 1392/4885
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi DPM1, CROCC, SNX1 KAT6A 4479/4885HTT 2598/4885MAPT 1392/4885
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB KAT6A 4357/4885HTT 2375/4885MAPT 2644/4885
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB KAT6A 4357/4885HTT 2375/4885MAPT 2644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.