Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16207488 | 0.81 | AAK1 (0.38) | MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL16216369 | 0.80 | MAOB (0.35) | TSHRCA12CA7CA9CA14 | |
| SCHEMBL16219341 | 0.80 | PTGS1 (0.44) | TSHRCA12CA7CA9CA14 | |
| SCHEMBL16207491 | 0.80 | PTGS1 (0.44) | TSHRCA12CA7CA9CA14 | |
| SCHEMBL16207383 | 0.80 | TAS1R3 (0.40) | TSHRCA12CA7CA9CA14 | |
| SCHEMBL16207444 | 0.78 | PTGS1 (0.36) | TSHRCA12CA7CA9CA14 | |
| SCHEMBL16207392 | 0.74 | GAA (0.40) | MEN1KMT2AGAA | |
| SCHEMBL16585353 | 0.74 | KMT2A (0.47) | MEN1KMT2APTGS1PTGS2GAA | |
| SCHEMBL16216461 | 0.73 | MAOB (0.37) | TSHRMAOBMEN1KMT2APTGS1 | |
| SCHEMBL16207546 | 0.73 | MAOB (0.37) | TSHRMAOBMEN1KMT2APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799424-B1 | 2-FLUOROPHENYLPROPIONIC ACID DERIVATIVE | LTT BIO PHARMA CO LTD (JP) | 2016-08-17 | — | — | EP | disclosed |
| US-9221786-B2 | 2-fluorophenyl propionic acid derivatives | LTT BIO-PHARMA CO., LTD. (JP) | 2015-12-29 | — | — | US | disclosed |
| US-9221786-B2 | 2-fluorophenyl propionic acid derivatives | LTT BIO-PHARMA CO., LTD. (JP) | 2015-12-29 | — | — | US | disclosed |
| US-9221786-B2 | 2-fluorophenyl propionic acid derivatives | LTT BIO-PHARMA CO., LTD. (JP) | 2015-12-29 | — | — | US | disclosed |
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | LTT BIO-PHARMA CO., LTD. (JP) | 2014-11-06 | — | — | US | disclosed |
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | LTT BIO-PHARMA CO., LTD. (JP) | 2014-11-06 | — | — | US | disclosed |
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | LTT BIO-PHARMA CO., LTD. (JP) | 2014-11-06 | — | — | US | disclosed |
| EP-2799424-A1 | 2-FLUOROPHENYLPROPIONIC ACID DERIVATIVE | LTT Bio-Pharma Co., Ltd. (JP) | 2014-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330026-A1 | 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES | FPR1, OPRK1, FPR2 | TSHR 1399/4885CA12 1565/4885CA7 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.