SCHEMBL16207488

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16207383	0.84	TAS1R3 (0.40)	PTGS1PTGS2MEN1KMT2ASMN1; SMN2
	SCHEMBL16207444	0.82	PTGS1 (0.36)	PTGS1PTGS2MEN1KMT2ASMN1; SMN2
	SCHEMBL16207458	0.81	TSHR (0.35)	PTGS1PTGS2MEN1KMT2A
	SCHEMBL16207545	0.80	SMN1; SMN2 (0.40)	ALDH1A1PTGS1PTGS2NOTUMMEN1
	SCHEMBL28915928	0.79	AKR1C3 (0.40)	PTGS1PTGS2MEN1KMT2ALMNA
	SCHEMBL20681094	0.79	SLC6A3 (0.37)	ALDH1A1PTGS1PTGS2MEN1KMT2A
	SCHEMBL16207392	0.78	GAA (0.40)	ALDH1A1L3MBTL1MEN1KMT2ALMNA
	SCHEMBL2130305	0.78	APLNR (0.50)	AAK1ALDH1A1L3MBTL1PTGS1PTGS2
	SCHEMBL16585353	0.78	KMT2A (0.47)	ALDH1A1PTGS1PTGS2MEN1KMT2A
	SCHEMBL16554601	0.77	ERN1 (0.37)	ALDH1A1L3MBTL1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.