Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.48 |
| ▸ | DRD1 | P21728 | 5/20 | 0.48 |
| ▸ | DRD5 | P21918 | 4/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL163037 | 0.90 | LMNA (0.47) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL164258 | 0.89 | LMNA (0.42) | DRD2DRD1DRD5DRD3DRD4 | |
| Nitric Acid SCHEMBL161325 | 0.87 | DRD1 (0.41) | DRD2DRD1DRD5DRD3DRD4 | |
| Malonic Acid SCHEMBL161793 | 0.86 | OPRM1 (0.43) | DRD5PRCP | |
| Glycolic Acid SCHEMBL158529 | 0.86 | KDM4E (0.41) | DRD2DRD1DRD5DRD3DRD4 | |
| Adipic Acid SCHEMBL160638 | 0.84 | KDM4E (0.46) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL19121066 | 0.78 | DRD2 (0.55) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL17662597 | 0.78 | DRD2 (0.55) | DRD2DRD1DRD5DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL11458075 | 0.77 | DRD2 (0.54) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL3697297 | 0.74 | DRD2 (0.46) | DRD2DRD1DRD5DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611781-A1 | FAST-DISSOLVE DOSAGE FORMS OF 5-HT2C AGONISTS | Arena Pharmaceuticals, Inc. (US) | 2013-07-10 | — | — | EP | claimed |
| WO-2012030951-A1 | FAST-DISSOLVE DOSAGE FORMS OF 5-HT2C AGONISTS | ARENA PHARMACEUTICALS, INC. (US) | 2012-03-08 | — | — | WO | claimed |