Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL158529 | 0.91 | KDM4E (0.41) | OPRM1OPRK1KDM4EMEN1POLB | |
| Adipic Acid SCHEMBL160638 | 0.89 | KDM4E (0.46) | OPRM1OPRK1KDM4EMEN1POLB | |
| SCHEMBL162104 | 0.86 | DRD2 (0.48) | DRD5PRCP | |
| SCHEMBL164258 | 0.85 | LMNA (0.42) | OPRM1OPRK1NOTUMDRD5PRCP | |
| Sulfuric Acid SCHEMBL163037 | 0.84 | LMNA (0.47) | OPRM1OPRK1KDM4ENOTUMDRD5 | |
| Nitric Acid SCHEMBL161325 | 0.81 | DRD1 (0.41) | OPRM1OPRK1MEN1POLBMAPT | |
| Malonic Acid SCHEMBL160931 | 0.72 | HDAC1 (0.50) | KDM4EMEN1POLBMAPTKMT2A | |
| Succinic Acid SCHEMBL170445 | 0.70 | DRD2 (0.64) | KDM4EMEN1POLBMAPTKMT2A | |
| SCHEMBL5332110 | 0.68 | OPRM1 (0.57) | OPRM1OPRK1KDM4EMEN1POLB | |
| SCHEMBL17662597 | 0.68 | DRD2 (0.55) | DRD5PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611781-A1 | FAST-DISSOLVE DOSAGE FORMS OF 5-HT2C AGONISTS | Arena Pharmaceuticals, Inc. (US) | 2013-07-10 | — | — | EP | claimed |
| WO-2012030951-A1 | FAST-DISSOLVE DOSAGE FORMS OF 5-HT2C AGONISTS | ARENA PHARMACEUTICALS, INC. (US) | 2012-03-08 | — | — | WO | claimed |