Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.46 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.46 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.46 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16232251 | 0.84 | KMT2A (0.61) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL16227467 | 0.83 | CTSS (0.59) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL16227142 | 0.82 | CTSS (0.64) | KMT2ASMN1; SMN2 | |
| SCHEMBL18856912 | 0.80 | CNR1 (0.49) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL13812597 | 0.77 | THRB (0.58) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6716502 | 0.76 | MEN1 (0.79) | NPC1RAB9AKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL1437584 | 0.76 | FFAR1 (0.65) | KMT2AMEN1BCHEFFAR1FFAR4 | |
| SCHEMBL11612611 | 0.72 | POLB (0.62) | RAB9AKMT2AMEN1LMNA | |
| SCHEMBL8575115 | 0.72 | LTA4H (0.63) | BCHEFFAR1FFAR4EPHX2 | |
| SCHEMBL9668580 | 0.72 | EPHX2 (0.62) | KMT2AMEN1BCHEFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140336503-A1 | RADIOLABELED BIOMARKERS FOR OSTEOCLAST ACTIVATION AND RELATED METHODS THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-11-13 | — | — | US | disclosed |
| US-20140336503-A1 | RADIOLABELED BIOMARKERS FOR OSTEOCLAST ACTIVATION AND RELATED METHODS THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336503-A1 | RADIOLABELED BIOMARKERS FOR OSTEOCLAST ACTIVATION AND RELATED METHODS THEREOF | CTSK, CTSF, CTSB | NPC1 270/4885RAB9A 509/4885KMT2A 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.