Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL27605584 | 0.82 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL15058500 | 0.82 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL28606614 | 0.82 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL28483577 | 0.79 | GPR84 (0.61) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL2352469 | 0.77 | PLA2G2A (0.51) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL30725643 | 0.75 | GPR84 (0.65) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL2363167 | 0.75 | PLA2G2A (0.49) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL10885528 | 0.75 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL9442061 | 0.75 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL1143367 | 0.75 | GPR84 (0.77) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109280306-B | Preparation method of polymethacrylimide composite foam conductive wave-absorbing material | 浙江中科恒泰新材料科技有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-108570207-B | Preparation method of high-strength automobile new material | 博兴融智科技创新发展有限公司 | 2020-12-15 | — | — | CN | claimed |
| CN-108869233-A | A kind of small-sized pressure stabilizing long axis Fire Fighting Pumps using novel coolant | 贝德科技有限公司 | 2018-11-23 | — | — | CN | claimed |
| EP-4007561-A1 | PREVENTION AND REDUCTION OF CORNIFICATION DISORDERS AND RELATED COSMETIC AGENTS | Merck Patent GmbH (DE) | 2022-06-08 | — | — | EP | disclosed |
| CN-109280306-B | Preparation method of polymethacrylimide composite foam conductive wave-absorbing material | 浙江中科恒泰新材料科技有限公司 | 2021-04-13 | — | — | CN | disclosed |
| WO-2021018990-A1 | PREVENTION AND REDUCTION OF CORNIFICATION DISORDERS AND RELATED COSMETIC AGENTS | MERCK PATENT GMBH (DE) | 2021-02-04 | — | — | WO | disclosed |
| US-10893675-B2 | Powder formulation containing insect repellent | MERCK PATENT GMBH (DE) | 2021-01-19 | — | — | US | disclosed |
| CN-108570207-B | Preparation method of high-strength automobile new material | 博兴融智科技创新发展有限公司 | 2020-12-15 | — | — | CN | disclosed |
| CN-108485219-B | Preparation method of bio-based wood-plastic composite new material | 安徽中科达美新材料科技有限公司 | 2020-12-11 | — | — | CN | disclosed |
| US-20200030214-A1 | USE OF COMPATIBLE SOLUTES | MERCK PATENT GMBH (DE) | 2020-01-30 | — | — | US | disclosed |
| CN-108869233-A | A kind of small-sized pressure stabilizing long axis Fire Fighting Pumps using novel coolant | 贝德科技有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-104010525-B | Cyclohexanol derivative as antibacterial anti-microbial active matter purposes | 默克专利股份有限公司 | 2017-08-25 | — | — | CN | disclosed |
| US-9492364-B2 | Use of cyclohexanol derivatives as antimicrobial active compounds | MERCK PATENT GMBH (DE) | 2016-11-15 | — | — | US | disclosed |
| US-20160326091-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-11-10 | — | — | US | disclosed |
| US-9181161-B2 | Use of dicyclohexylmethanol derivatives having antimicrobial properties | MERCK PATENT GMBH (DE) | 2015-11-10 | — | — | US | disclosed |
| US-20150118165-A1 | USE OF CYCLOHEXANOL ETHERS HAVING ANTIMICROBIAL PROPERTIES | MERCK PATENT GMBH (DE) | 2015-04-30 | — | — | US | disclosed |
| US-20150118172-A1 | USE OF DICYCLOHEXYLMETHANOL DERIVATIVES HAVING ANTIMICROBIAL PROPERTIES | MERCK PATENT GMBH (DE) | 2015-04-30 | — | — | US | disclosed |
| CN-104487047-A | Use of cyclohexanol ethers having antimicrobial properties | MERCK PATENT GMBH | 2015-04-01 | — | — | CN | disclosed |
| CN-104271109-A | Use of dicyclohexylmethanol derivatives with antimicrobial properties | MERCK PATENT GMBH | 2015-01-07 | — | — | CN | disclosed |
| US-20140335029-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | MERCK PATENT GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200030214-A1 | USE OF COMPATIBLE SOLUTES | SLC9A5, SLC9A1, SLC9A3 | GPR84 3990/4885PPARG 4309/4885PPARD 4509/4885 |
| US-20140335029-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | CYP51A1, DDT, EBP | GPR84 3959/4885PPARG 527/4885PPARD 194/4885 |
| US-20150118172-A1 | USE OF DICYCLOHEXYLMETHANOL DERIVATIVES HAVING ANTIMICROBIAL PROPERTIES | DDT, DEK, EBP | GPR84 4431/4885PPARG 291/4885PPARD 133/4885 |
| US-20150118165-A1 | USE OF CYCLOHEXANOL ETHERS HAVING ANTIMICROBIAL PROPERTIES | EBP, CYP51A1, DECR2 | GPR84 3350/4885PPARG 154/4885PPARD 36/4885 |
| US-10893675-B2 | Powder formulation containing insect repellent | WAPL, ACHE, BPHL | GPR84 2774/4885PPARG 4351/4885PPARD 4502/4885 |
| US-20160326091-A1 | USE OF CYCLOHEXANOL DERIVATIVES AS ANTIMICROBIAL ACTIVE COMPOUNDS | CYP51A1, DDT, EBP | GPR84 3959/4885PPARG 527/4885PPARD 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.