Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 4/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16784656 | 0.93 | SLC6A9 (0.35) | SLC6A9SLC2A1 | |
| SCHEMBL16229747 | 0.90 | SLC6A9 (0.43) | SLC6A9KCNH2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16229785 | 0.90 | DGAT1 (0.36) | SLC6A9KCNH2TAAR1SMN1; SMN2 | |
| SCHEMBL16784655 | 0.88 | SLC6A9 (0.50) | SLC6A9KCNH2 | |
| SCHEMBL16229756 | 0.88 | SLC6A9 (0.32) | SLC6A9TBXA2RKCNH2AKR1C3EPHX2 | |
| SCHEMBL16229808 | 0.88 | GALR3 (0.42) | SLC6A9KCNH2 | |
| SCHEMBL16229776 | 0.87 | SLC6A9 (0.36) | SLC6A9SLC2A1TBXA2RAKR1C3EPHX2 | |
| SCHEMBL16784628 | 0.83 | SLC6A9 (0.44) | SLC6A9KCNH2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16229783 | 0.83 | SLC6A9 (0.41) | SLC6A9TBXA2RAKR1C3MAPT | |
| SCHEMBL16784642 | 0.83 | SLC6A9 (0.35) | SLC6A9KCNH2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051280-B2 | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-06-09 | — | — | US | disclosed |
| US-8883839-B2 | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy | ABBOTT LABORATORIES (US) | 2014-11-11 | — | — | US | disclosed |