Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 9/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 9/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18797369 | 0.76 | KMT2A (0.40) | ADRA2AADRA2BADRA2CESR1ESR2 | |
| SCHEMBL16229870 | 0.76 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CESR1ESR2 | |
| SCHEMBL16229860 | 0.73 | ESR2 (0.52) | CA4CA6CA5ACA7ENPP2 | |
| SCHEMBL29739463 | 0.72 | MAPT (0.37) | ADRA2AADRA2BADRA2CPLAU | |
| SCHEMBL2729935 | 0.71 | ADRA2A (0.59) | ADRA2AADRA2BADRA2CPLAU | |
| SCHEMBL24068036 | 0.70 | RAB9A (0.36) | ADRA2AADRA2BADRA2CESR1ESR2 | |
| SCHEMBL31507859 | 0.70 | CYP19A1 (0.34) | ADRA2AADRA2BADRA2CESR1ESR2 | |
| SCHEMBL30339156 | 0.70 | RAB9A (0.36) | ADRA2AADRA2BADRA2CESR1ESR2 | |
| SCHEMBL21355585 | 0.69 | KMT2A (0.43) | ADRA2AADRA2BADRA2CESR2 | |
| SCHEMBL31508095 | 0.69 | ABL1 (0.33) | ADRA2AADRA2BADRA2CESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305937-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AMRI ITALY S.R.L. (IT) | 2017-10-26 | — | — | US | disclosed |
| US-20170305937-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AMRI ITALY S.R.L. (IT) | 2017-10-26 | — | — | US | disclosed |
| US-9738663-B2 | Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters | EUTICALS S.P.A. (IT) | 2017-08-22 | — | — | US | disclosed |
| US-9738663-B2 | Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters | EUTICALS S.P.A. (IT) | 2017-08-22 | — | — | US | disclosed |
| EP-2994473-B1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | EUTICALS SPA (IT) | 2016-12-21 | — | — | EP | disclosed |
| US-20160075723-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AMRI ITALY S.R.L. (IT) | 2016-03-17 | — | — | US | disclosed |
| EP-2801577-A1 | Process for the preparation of aminoaryl- and aminoheteroaryl boronic acids and esters | Euticals S.P.A. (IT) | 2014-11-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305937-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AADAT, BCAT2, BCAT1 | CA4 1326/4885CA6 213/4885CA5A 2459/4885 |
| US-20160075723-A1 | PROCESS FOR THE PREPARATION OF AMINOARYL- AND AMINOHETEROARYL BORONIC ACIDS AND ESTERS | AADAT, BCAT2, BCAT1 | CA4 1463/4885CA6 301/4885CA5A 1805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.