Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | FABP7 | O15540 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3857751 | 0.98 | KMT2A (0.47) | KMT2AMEN1THRATHRBSMN1; SMN2 | |
| SCHEMBL505224 | 0.88 | THRA (0.49) | THRATHRBRAB9AKDM4ECYP1A2 | |
| SCHEMBL27737478 | 0.86 | THRA (0.47) | THRATHRBRAB9AKDM4ECYP1A2 | |
| SCHEMBL27737348 | 0.86 | THRA (0.47) | THRATHRBRAB9AKDM4ECYP1A2 | |
| SCHEMBL9190844 | 0.86 | THRA (0.47) | THRATHRBRAB9AKDM4ECYP1A2 | |
| SCHEMBL3291890 | 0.85 | THRB (0.47) | KMT2AMEN1THRATHRBLMNA | |
| SCHEMBL3858464 | 0.83 | THRB (0.46) | KMT2AMEN1THRATHRBSMN1; SMN2 | |
| SCHEMBL11011114 | 0.81 | ELANE (0.62) | KMT2AMEN1NPC1GAATDP1 | |
| SCHEMBL28140863 | 0.81 | THRA (0.44) | THRATHRBRAB9AKDM4ECYP1A2 | |
| Tetramethylammonium Ion SCHEMBL27737350 | 0.81 | THRB (0.47) | KMT2AMEN1THRATHRBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839690-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2017-12-12 | — | — | US | disclosed |
| US-9839690-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2017-12-12 | — | — | US | disclosed |
| US-20170014510-A1 | Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2017-01-19 | — | — | US | disclosed |
| US-20170014510-A1 | Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2017-01-19 | — | — | US | disclosed |
| EP-2611771-B1 | SUBSTITUTED HETEROARYL- AND ARYLALKYNYL BENZENE DERIVATIVES AS ACC-INHIBITORS FOR THE TREATMENT OF METABOLIC DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2016-11-23 | — | — | EP | disclosed |
| US-9393306-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2016-07-19 | — | — | US | disclosed |
| US-9393306-B2 | Singlet oxygen-labile linkers and methods of production and use thereof | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150165026-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2015-06-18 | — | — | US | disclosed |
| US-20150165026-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2015-06-18 | — | — | US | disclosed |
| US-8835472-B2 | Compounds, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-16 | — | — | US | disclosed |
| WO-2013163321-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | YOU YOUNGJAE (US) | 2013-10-31 | — | — | WO | disclosed |
| EP-2611771-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| US-20120214785-A1 | New compounds, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-23 | — | — | US | disclosed |
| WO-2012028676-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |
| US-7592373-B2 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-09-22 | — | — | US | disclosed |
| US-20050267093-A1 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170014510-A1 | Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof | PPOX, DUOX1, PAICS | KMT2A 2599/4885MEN1 2293/4885THRA 4448/4885 |
| US-20120214785-A1 | New compounds, pharmaceutical compositions and uses thereof | ABCG2, PGA5, PDE6G | KMT2A 4647/4885MEN1 500/4885THRA 4402/4885 |
| US-20150165026-A1 | SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF | PPOX, DUOX1, PAICS | KMT2A 2599/4885MEN1 2293/4885THRA 4448/4885 |
| US-20050267093-A1 | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds | MCHR1, MC4R, MCHR2 | KMT2A 678/4885MEN1 807/4885THRA 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.