Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1358288 | 0.86 | KDM4E (0.63) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL30728866 | 0.85 | TUBB4A (0.49) | KDM4EHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL16719162 | 0.83 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL16719154 | 0.82 | CFD (0.68) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL16719164 | 0.82 | MAPK1 (0.61) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL28876287 | 0.81 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL268963 | 0.80 | L3MBTL1 (0.59) | KDM4EHSD17B10ALDH1A1AKR1C2AKR1C1 | |
| SCHEMBL30361685 | 0.80 | L3MBTL1 (0.59) | KDM4EHSD17B10ALDH1A1AKR1C2AKR1C1 | |
| SCHEMBL16247703 | 0.79 | AKR1C2 (0.51) | ALDH1A1HPGDAKR1C2AKR1C1CNR2 | |
| SCHEMBL10420497 | 0.78 | KDM4E (0.84) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238637-B2 | Stable polymorphic forms of compound as hypoxia mimetics, and uses thereof | BEIJING BETTA PHARMACEUTICALS CO., LTD (CN) | 2016-01-19 | — | — | US | disclosed |
| US-20140343137-A1 | Stable Polymorphic Forms of Compound as Hypoxia Mimetics, and Uses Thereof | BEIJING BETTA PHARMACEUTICALS CO., LTD. (CN) | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343137-A1 | Stable Polymorphic Forms of Compound as Hypoxia Mimetics, and Uses Thereof | HIF1A, HIF1AN, COXFA4L2 | KDM4E 3960/4885HSD17B10 1007/4885ALDH1A1 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.