SCHEMBL16255504

SCHEMBL16255504

CCCCOc1nc(Cl)nc(Oc2ccccc2)n1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.56
PAX8 Q06710 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
KDM4E B2RXH2 1/20 0.40
TLR7 Q9NYK1 4/20 0.39
IL6 P05231 1/20 0.39
NPC1 O15118 1/20 0.39
GAA P10253 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14971446 0.92 LTA4H (0.65) LTA4HPAX8MEN1KMT2AALDH1A1
SCHEMBL6051629 0.83 RAB9A (0.41) LTA4HKDM4ETLR7NPC1RAB9A
SCHEMBL49317 0.82 PAX8 (0.53) LTA4HPAX8MEN1KMT2AALDH1A1
SCHEMBL1318906 0.80 RAB9A (0.41) LTA4HALDH1A1KDM4ETLR7NPC1
SCHEMBL29106791 0.79 TLR7 (0.44) LTA4HALDH1A1KDM4ETLR7NPC1
SCHEMBL16086043 0.78 PIN1 (0.43) PAX8MEN1KMT2AKDM4ENPC1
SCHEMBL1639470 0.78 KDM4E (0.50) LTA4HPAX8MEN1KMT2AALDH1A1
SCHEMBL11859472 0.77 MEN1 (0.53) LTA4HPAX8MEN1KMT2AALDH1A1
SCHEMBL32688290 0.77 MEN1 (0.53) LTA4HPAX8MEN1KMT2AALDH1A1
SCHEMBL10642577 0.77 CYP1A2 (0.47) LTA4HGAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2781511-B1 HYDROXY GROUP PROTECTING AGENT AND HYDROXY GROUP PROTECTION METHOD UNIV NAT CORP KANAZAWA (JP) 2017-12-20 EP disclosed
US-9126954-B2 Hydroxy group protecting agent and hydroxy group protection method NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) 2015-09-08 US disclosed
US-20140343281-A1 HYDROXY GROUP PROTECTING AGENT AND HYDROXY GROUP PROTECTION METHOD NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) 2014-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140343281-A1 HYDROXY GROUP PROTECTING AGENT AND HYDROXY GROUP PROTECTION METHOD OGG1, HAO2, HAAO LTA4H 490/4885PAX8 2464/4885MEN1 1779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.