Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16259491 | 0.90 | MAPT (0.55) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL28854422 | 0.82 | ALDH1A1 (0.51) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL7951394 | 0.82 | MAPT (1.00) | MAPTALDH1A1KMT2AHTTRAB9A | |
| SCHEMBL13155174 | 0.82 | HDAC8 (0.59) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL2346923 | 0.81 | GPR35 (0.47) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL10201044 | 0.80 | NPC1 (0.68) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL14200242 | 0.79 | ALDH1A1 (0.60) | MAPTALDH1A1SMN1; SMN2KMT2AHTT | |
| SCHEMBL16448816 | 0.79 | SMN1; SMN2 (0.62) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7758352 | 0.78 | KIF11 (0.59) | MAPTALDH1A1NPC1HDAC3HDAC6 | |
| SCHEMBL27799352 | 0.76 | SMN1; SMN2 (0.47) | MAPTALDH1A1SMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640462-B2 | Oil gelator | NATIONAL UNIVERSITY CORPORATION SHIZUOKA UNIVERSITY (JP) | 2020-05-05 | — | — | US | disclosed |
| US-9085548-B2 | Pseudorotaxanes, rotaxanes and catenanes formed by metal ions templating | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-07-21 | — | — | US | disclosed |
| US-20150051393-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-02-19 | — | — | US | disclosed |
| US-20140350242-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | NATIONAL TAIWAN UNIVERSITY (TW) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10640462-B2 | Oil gelator | MGLL, CCNL2, CCNI | MAPT 3832/4885ALDH1A1 593/4885SMN1; SMN2 3638/4885 |
| US-20150051393-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | PCNA, TIMCC, SGTA | MAPT 642/4885ALDH1A1 4300/4885SMN1; SMN2 4506/4885 |
| US-20140350242-A1 | PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING | PCNA, TIMCC, SGTA | MAPT 642/4885ALDH1A1 4300/4885SMN1; SMN2 4506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.