SCHEMBL16267516

SCHEMBL16267516

C=Cc1ccc(C(=O)OC2CCC(C)(C)N(C)C2(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SCN1A P35498 2/20 0.36
SCN2A Q99250 2/20 0.36
SCN3A Q9NY46 2/20 0.36
POLB P06746 1/20 0.34
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
TSHR P16473 1/20 0.33
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
CHRNA7 P36544 1/20 0.33
HTR3A P46098 1/20 0.33
HTR3D Q70Z44 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11320172 0.81 KMT2A (0.40) KMT2AMAPTMAPK1RAB9ASMN1; SMN2
SCHEMBL16273220 0.77 TSHR (0.49) KMT2ASCN1ASCN2ASCN3APOLB
SCHEMBL2202765 0.74 TSHR (0.30) CYP2C19TSHR
SCHEMBL3722353 0.70 TSHR (0.47) KMT2AMAPTMAPK1SCN1ASCN2A
SCHEMBL9370902 0.70 TSHR (0.47) KMT2AMAPTMAPK1SCN1ASCN2A
SCHEMBL26807768 0.70 PTPN2 (0.46) KMT2AMAPTMAPK1SCN1ASCN2A
Pempidine SCHEMBL28985609 0.70 NFKB1 (0.49) KMT2AMAPTNPC1RAB9ASMN1; SMN2
SCHEMBL16267519 0.67 MCL1 (0.34)
SCHEMBL8147768 0.66 SMN1; SMN2 (0.37) SMN1; SMN2
SCHEMBL14527796 0.66 CYP19A1 (0.38) KMT2AMAPTMAPK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486352-B2 Composition, and optical material and lens using same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-12-02 US disclosed
US-20230374191-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-11-23 US disclosed
US-20230339921-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAID COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-10-26 US disclosed
EP-4230616-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAID COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-08-23 EP disclosed
EP-4206187-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-07-05 EP disclosed
EP-3088441-B1 OPTICAL MATERIAL COMPOSITION AND METHOD FOR PRODUCING SAME MITSUBISHI GAS CHEMICAL CO (JP) 2019-02-20 EP disclosed
US-9658365-B2 Optical material composition and method for producing same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-05-23 US disclosed
US-9529117-B2 Polymerizable composition for optical material, method for producing same, and method for producing optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-12-27 US disclosed
US-9518153-B2 Polymerizable composition for optical materials MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-12-13 US disclosed
EP-3088441-A1 OPTICAL MATERIAL COMPOSITION AND METHOD FOR PRODUCING SAME Mitsubishi Gas Chemical Company, Inc. (JP) 2016-11-02 EP disclosed
US-20160259091-A1 OPTICAL MATERIAL COMPOSITION AND METHOD FOR PRODUCING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2016-09-08 US disclosed
EP-2816070-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2016-08-17 EP disclosed
US-20150011727-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-01-08 US disclosed
EP-2816070-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING OPTICAL MATERIAL Mitsubishi Gas Chemical Company, Inc. (JP) 2014-12-24 EP disclosed
US-20140357835-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339921-A1 COMPOSITION, AND OPTICAL MATERIAL AND LENS USING SAID COMPOSITION CRYAA, UACA, CRYZ KMT2A 1143/4885MAPT 144/4885MAPK1 3740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.