Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL382260 | 1.00 | TSHR (0.42) | TSHRTP53CA1CA2CA9 | |
| Hydrogen Peroxide SCHEMBL28403802 | 0.88 | ALDH1A1 (0.33) | TSHRTP53CA1CA2CA9 | |
| SCHEMBL1627200 | 0.83 | TSHR (0.36) | TSHRTP53HCAR2ALDH1A1KMT2A | |
| SCHEMBL45125 | 0.78 | — | — | |
| Bicarbonate SCHEMBL28488934 | 0.77 | TSHR (0.42) | TSHRTP53CA1CA2CA9 | |
| Bicarbonate SCHEMBL700909 | 0.77 | TSHR (0.42) | TSHRTP53CA1CA2CA9 | |
| Bicarbonate SCHEMBL95011 | 0.77 | TSHR (0.42) | TSHRTP53CA1CA2CA9 | |
| SCHEMBL28532897 | 0.76 | TP53 (0.36) | TSHRTP53HCAR2SLC7A5 | |
| SCHEMBL8980007 | 0.76 | — | — | |
| Benzene SCHEMBL471823 | 0.75 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11781049-B2 | Adhesive glue, curing method therefor, and application thereof | SAE MAGNETICS (H.K.) LTD. (CN) | 2023-10-10 | — | — | US | claimed |
| US-20230151254-A1 | ADHESIVE GLUE, CURING METHOD THEREFOR, AND APPLICATION THEREOF | SAE MAGNETICS (H.K.) LTD. (CN) | 2023-05-18 | — | — | US | claimed |
| CN-115386035-A | High-performance damping vibration attenuation elastomer based on multistage energy dissipation mechanism and preparation method thereof | 四川大学 | 2022-11-25 | — | — | CN | claimed |
| US-10947189-B2 | Online continuous flow process for the synthesis of organic peroxides using hydrogen peroxide as raw material | SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) | 2021-03-16 | — | — | US | claimed |
| WO-2020238246-A1 | VINYLIDENE FLUORIDE POLYMER FOR LITHIUM ION POWER BATTERY BINDER, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江孚诺林化工新材料有限公司 | 2020-12-03 | — | — | WO | claimed |
| EP-3666755-A1 | ONLINE FULL CONTINUOUS FLOW PRODUCTION PROCESS FOR DIRECTLY PREPARING ORGANIC PEROXIDE WITH HYDROGEN PEROXIDE AS RAW MATERIAL | Shanghai Hybrid-Chem Technologies (CN) | 2020-06-17 | — | — | EP | claimed |
| US-20200172478-A1 | ONLINE CONTINUOUS FLOW PROCESS FOR THE SYNTHESIS OF ORGANIC PEROXIDES USING HYDROGEN PEROXIDE AS RAW MATERIAL | SHANGHAI HYBRID-CHEM TECHNOLOGIES (CN) | 2020-06-04 | — | — | US | claimed |
| CN-119192434-B | Method for separating low molecular weight impurities from perfluoroether elastomer emulsion | 上海森桓新材料科技有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119192434-A | Method for separating low molecular weight impurities from perfluoroether elastomer emulsion | 上海森桓新材料科技有限公司 | 2024-12-27 | — | — | CN | disclosed |
| US-20240343926-A1 | COLORED RESIN COMPOSITION, COLORED RESIN COMPOSITION SET, AND COLOR FILTER | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-10-17 | — | — | US | disclosed |
| CN-117926573-A | Functional artificial grass fiber and manufacturing method thereof | 江苏文明人造草坪有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117916223-A | Method for producing tetrafluorothio-containing aryl compound | ＡＧＣ株式会社 | 2024-04-19 | — | — | CN | disclosed |
| US-11781049-B2 | Adhesive glue, curing method therefor, and application thereof | SAE MAGNETICS (H.K.) LTD. (CN) | 2023-10-10 | — | — | US | disclosed |
| EP-0113061-A2 | Copolymer containing isocyanate groups | BASF Aktiengesellschaft (DE) | 1984-07-11 | — | — | EP | disclosed |
| EP-0021014-B1 | VARNISH BINDERS AND THEIR USE IN ELECTRODIPPING VARNISHES | BASF Aktiengesellschaft (DE) | 1982-10-20 | — | — | EP | disclosed |
| EP-0007531-B1 | VINYL CHLORIDE COPOLYMERS CONTAINING CARBOXYL GROUPS AND USE THEREOF | BASF Aktiengesellschaft (DE) | 1981-11-11 | — | — | EP | disclosed |
| US-4297519-A | Process for the preparation of 2-nitrobenzaldehyde | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-27 | — | — | US | disclosed |
| EP-0030524-A2 | A method of polymerizing vinyl chloride | NORSK HYDRO A/S (NO) | 1981-06-17 | — | — | EP | disclosed |
| EP-0021014-A1 | Varnish binders and their use in electrodipping varnishes | BASF Aktiengesellschaft (DE) | 1981-01-07 | — | — | EP | disclosed |
| EP-0007531-A1 | Vinyl chloride copolymers containing carboxyl groups and use thereof | BASF Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947189-B2 | Online continuous flow process for the synthesis of organic peroxides using hydrogen peroxide as raw material | PPOX, HAO2, AOX1 | TSHR 3880/4885TP53 4477/4885CA1 2926/4885 |
| US-20200172478-A1 | ONLINE CONTINUOUS FLOW PROCESS FOR THE SYNTHESIS OF ORGANIC PEROXIDES USING HYDROGEN PEROXIDE AS RAW MATERIAL | PPOX, HAO2, AOX1 | TSHR 3880/4885TP53 4477/4885CA1 2926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.