Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16279742 | 0.75 | — | — | |
| SCHEMBL25230246 | 0.73 | ALDH1A1 (0.46) | — | |
| SCHEMBL31015963 | 0.73 | ALDH1A1 (0.46) | — | |
| SCHEMBL10431976 | 0.70 | CYP2A6 (0.47) | IDO1 | |
| SCHEMBL16284423 | 0.70 | BCKDK (0.40) | — | |
| SCHEMBL16279379 | 0.70 | MCL1 (0.42) | — | |
| SCHEMBL16934966 | 0.68 | KDM4E (0.31) | — | |
| SCHEMBL3689291 | 0.67 | NPSR1 (0.37) | — | |
| SCHEMBL3687153 | 0.67 | GPR35 (0.59) | — | |
| SCHEMBL3683131 | 0.67 | CYP2A6 (0.52) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9399038-B2 | Benzothiophene compound | ASTELLAS PHARMA INC. (JP) | 2016-07-26 | — | — | US | disclosed |
| US-9399038-B2 | Benzothiophene compound | ASTELLAS PHARMA INC. (JP) | 2016-07-26 | — | — | US | disclosed |
| US-20150133433-A1 | BENZOTHIOPHENE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2015-05-14 | — | — | US | disclosed |
| US-20150133433-A1 | BENZOTHIOPHENE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2015-05-14 | — | — | US | disclosed |
| US-8981119-B2 | Benzothiophene compound | ASTELLAS PHARMA INC. (JP) | 2015-03-17 | — | — | US | disclosed |
| US-8981119-B2 | Benzothiophene compound | ASTELLAS PHARMA INC. (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20140364421-A1 | BENZOTHIOPHENE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-11 | — | — | US | disclosed |
| US-20140364421-A1 | BENZOTHIOPHENE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133433-A1 | BENZOTHIOPHENE COMPOUND | TRPA1, TRPV1, TRPV3 | GPR84 1568/4885IDO1 807/4885EGFR 4121/4885 |
| US-20140364421-A1 | BENZOTHIOPHENE COMPOUND | TRPA1, TRPV1, TRPV4 | GPR84 930/4885IDO1 153/4885EGFR 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.