Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23225677 | 1.00 | DGKA (0.50) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL28429625 | 1.00 | DGKA (0.50) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL1810800 | 0.97 | DGKA (0.46) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL8775788 | 0.93 | DGKA (0.45) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL30864611 | 0.91 | TSHR (0.55) | PAMTSHRLMNAALDH1A1MEN1 | |
| SCHEMBL10414846 | 0.89 | DGKA (0.69) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL23748843 | 0.89 | DGKA (0.69) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL355177 | 0.89 | DGKA (0.69) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL353797 | 0.89 | DGKA (0.69) | DGKAPAMTSHRMAPTLMNA | |
| SCHEMBL2857061 | 0.89 | DGKA (0.69) | DGKAPAMTSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220064106-A1 | NITRIC OXIDE DONORS | MEDCHEM PARTNERS LLC (US) | 2022-03-03 | — | — | US | disclosed |
| US-11148999-B2 | Nitric oxide donors | MedChem Partners, LLC (US) | 2021-10-19 | — | — | US | disclosed |
| US-20190345099-A1 | NITRIC OXIDE DONORS | MEDCHEM PARTNERS, LLC. | 2019-11-14 | — | — | US | disclosed |
| US-9907812-B2 | Conjugate-based antifungal and antibacterial prodrugs | VYOME BIOSCIENCES PVT. LTD. (IN) | 2018-03-06 | — | — | US | disclosed |
| US-20140364595-A1 | CONJUGATE-BASED ANTIFUNGAL AND ANTIBACTERIAL PRODRUGS | VYOME BIOSCIENCES (IN) | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190345099-A1 | NITRIC OXIDE DONORS | NOS2, NOS1, NOS3 | DGKA 2676/4885PAM 235/4885TSHR 2741/4885 |
| US-11148999-B2 | Nitric oxide donors | NOS2, NOS1, NOS3 | DGKA 2676/4885PAM 235/4885TSHR 2741/4885 |
| US-20140364595-A1 | CONJUGATE-BASED ANTIFUNGAL AND ANTIBACTERIAL PRODRUGS | XPO1, MTX1, FUT5 | DGKA 4600/4885PAM 103/4885TSHR 4597/4885 |
| US-20220064106-A1 | NITRIC OXIDE DONORS | NOS2, NOS1, NOS3 | DGKA 2676/4885PAM 235/4885TSHR 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.