SCHEMBL355177

SCHEMBL355177

CCCCCCCCCCCCCCCC(=O)OCCl

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.69
PAM P19021 2/20 0.62
TSHR P16473 2/20 0.58
MAPT P10636 1/20 0.58
LMNA P02545 4/20 0.56
ALDH1A1 P00352 2/20 0.56
DNM1 Q05193 1/20 0.56
KDM4E B2RXH2 1/20 0.55
DUSP3 P51452 1/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
PRKCA P17252 1/20 0.51
PRKCE Q02156 1/20 0.51
PRKCQ Q04759 1/20 0.51
PRKCD Q05655 1/20 0.51
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782819 1.00 DGKA (0.69) DGKAPAMTSHRMAPTLMNA
SCHEMBL29366771 1.00 DGKA (0.69) DGKAPAMTSHRMAPTLMNA
SCHEMBL10901771 1.00 DGKA (0.69) DGKAPAMTSHRMAPTLMNA
SCHEMBL2857061 1.00 DGKA (0.69) DGKAPAMTSHRMAPTLMNA
SCHEMBL28699910 1.00 DGKA (0.69) DGKAPAMTSHRMAPTLMNA
SCHEMBL6266491 1.00 DGKA (0.69) DGKAPAMTSHRMAPTLMNA
SCHEMBL10414846 1.00 DGKA (0.69) DGKAPAMTSHRMAPTLMNA
SCHEMBL353797 1.00 DGKA (0.69) DGKAPAMTSHRMAPTLMNA
SCHEMBL356145 1.00 DGKA (0.69) DGKAPAMTSHRMAPTLMNA
Heptanoic Acid Chloromethyl Ester SCHEMBL697729 1.00 DGKA (0.69) DGKAPAMTSHRMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240409466-A1 HIGH DENSITY WASHABLE MINING GROUTING REINFORCEMENT MATERIAL AND PREPARATION METHOD THEREOF CCRI (Beijing) New Material Technology Co., Ltd. (CN) 2024-12-12 US claimed
CN-114395320-B Chemical anti-sagging exposed single-component polyurethane waterproof coating and preparation method thereof 唐山东方雨虹防水技术有限责任公司 2023-02-17 CN claimed
CN-114395320-A Chemical anti-sagging exposed single-component polyurethane waterproof coating and preparation method thereof 唐山东方雨虹防水技术有限责任公司 2022-04-26 CN claimed
CN-122070276-A Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same 人类生物科学股份有限公司 2026-05-19 CN disclosed
EP-4705289-A1 PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF Terran Biosciences Inc. (US) 2026-03-11 EP disclosed
US-12570605-B2 Indole compounds, and preparation methods, and uses thereof SHENZHEN 01 LIFE SCIENCE AND TECHNOLOGY CO., LTD. (CN) 2026-03-10 US disclosed
US-20250282812-A1 ANTIVIRAL NUCLEOSIDE ANALOGUE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF VIGONVITA LIFE SCIENCES CO., LTD. (CN) 2025-09-11 US disclosed
US-12331068-B2 Compositions and methods for inhibiting CD73 PELOTON THERAPEUTICS, INC. (US) 2025-06-17 US disclosed
US-12269818-B2 Analogs of xanomeline TERRAN BIOSCIENCES INC. (US) 2025-04-08 US disclosed
EP-4512805-A1 ANTIVIRAL NUCLEOSIDE ANALOGUE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2025-02-26 EP disclosed
EP-4501926-A1 N-SUBSTITUTED QUINOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Vigonvita Life Sciences Co., Ltd. (CN) 2025-02-05 EP disclosed
US-5243043-A Cephalosporin antibiotics and bactericides ROUSSEL UCLAF (FR) 1993-09-07 US disclosed
US-4992431-A Bactericides or antibiotics ROUSSELUCLAF (FR) 1991-02-12 US disclosed
US-4727151-A CLEAVED TO DRUGS IN VIVO BY CHEMICAL OR ENZYMATIC HYDROLYSIS INTERX RESEARCH CORPORATION (US) 1988-02-23 US disclosed
US-4699925-A ANTIINFLAMMATORY AGENTS, ANALGESICS AND-OR ANTIPYRETICS KAKEN PHARMACEUTICAL CO., LTD. (JP) 1987-10-13 US disclosed
EP-0103265-B1 BIPHENYLYLPROPIONIC ACID DERIVATIVE, PROCESS FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME Kaken Pharmaceutical Co., Ltd. (JP) 1986-12-03 EP disclosed
EP-0103265-A2 Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same Kaken Pharmaceutical Co., Ltd. (JP) 1984-03-21 EP disclosed
US-4267326-A AS ANTITUMOR AGENTS MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1981-05-12 US disclosed
US-4160099-A Labile, non-heterocyclic quaternary ammonium salt/esters as transient derivatives INTERX RESEARCH CORPORATION 1979-07-03 US disclosed
US-4061722-A Selected quaternary ammonium salts of pilocarpine useful in reducing intraocular pressure in warm-blooded animals INTERX RESEARCH CORPORATION (US) 1977-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12269818-B2 Analogs of xanomeline HTR5A, HTR3A, HTR3B DGKA 2991/4885PAM 1063/4885TSHR 399/4885
US-12331068-B2 Compositions and methods for inhibiting CD73 ENTPD5, NT5E, ENTPD1 DGKA 2015/4885PAM 2776/4885TSHR 2778/4885
US-20250282812-A1 ANTIVIRAL NUCLEOSIDE ANALOGUE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF SAMHD1, PNP, NUDT1 DGKA 3635/4885PAM 531/4885TSHR 4461/4885
US-12570605-B2 Indole compounds, and preparation methods, and uses thereof IDO2, IDO1, TPH2 DGKA 2440/4885PAM 3927/4885TSHR 1333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.