SCHEMBL16289690

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16289363	0.86	ALDH1A1 (0.43)	MEN1MAPTKMT2ATSHRLMNA
	SCHEMBL7703302	0.67	MEN1 (0.82)	MEN1MAPTKMT2ATSHRLMNA
	SCHEMBL3799970	0.67	MAPT (0.46)	MEN1MAPTKMT2ATSHRLMNA
	SCHEMBL16289853	0.66	CRHBP (0.44)	TSHRLMNAALDH1A1TDP1HSD17B10
	SCHEMBL649172	0.64	CYP3A4 (0.49)	MAPTTSHRLMNAALDH1A1TDP1
	SCHEMBL645032	0.64	TSHR (0.45)	MAPTTSHRLMNAALDH1A1TDP1
	SCHEMBL16290034	0.64	TSHR (0.45)	MEN1MAPTKMT2ATSHRLMNA
	SCHEMBL10718955	0.64	MAPT (0.44)	MEN1MAPTKMT2ATSHRLMNA
	SCHEMBL7029620	0.64	CYP3A4 (0.49)	MEN1MAPTKMT2ATSHRALDH1A1
	SCHEMBL30349659	0.64	ALDH1A1 (0.52)	MEN1MAPTKMT2ATSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.