SCHEMBL7029620

SCHEMBL7029620

O=[N+]([O-])c1ccc2ncoc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.49
NAMPT P43490 1/20 0.49
XDH P47989 1/20 0.49
ALDH1A1 P00352 4/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
MAPT P10636 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
TXNRD1 Q16881 1/20 0.47
TXNRD3 Q86VQ6 1/20 0.47
TXNRD2 Q9NNW7 1/20 0.47
PARP1 P09874 1/20 0.44
DYRK1A Q13627 1/20 0.42
CYP1A2 P05177 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580246 0.86 ALDH1A1 (0.49) CYP3A4NAMPTXDHALDH1A1MEN1
SCHEMBL1607997 0.86 ALDH1A1 (0.49) CYP3A4NAMPTXDHALDH1A1MEN1
Hydrazine SCHEMBL27557478 0.83 ALDH1A1 (0.50) CYP3A4NAMPTXDHALDH1A1MEN1
SCHEMBL27971001 0.81 DHFR (0.44) CYP3A4NAMPTXDHALDH1A1MEN1
SCHEMBL28813152 0.78 PTPRF (0.51) ALDH1A1MEN1KMT2ASMN1; SMN2MAPT
Nitrobenzene SCHEMBL28594946 0.76 LMNA (0.53) ALDH1A1MEN1KMT2ASMN1; SMN2MAPT
Nitrobenzene SCHEMBL28018227 0.76 LMNA (0.53) ALDH1A1MEN1KMT2ASMN1; SMN2MAPT
SCHEMBL20741518 0.75 F7 (0.48) CYP3A4NAMPTXDHALDH1A1MEN1
SCHEMBL29216330 0.75 RAB9A (0.54) ALDH1A1MEN1KMT2ASMN1; SMN2MAPT
SCHEMBL11590947 0.74 LMNA (0.42) CYP3A4ALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0278509-B1 Silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 1996-01-24 EP claimed
US-4970141-A ELEVATED SPECTRAL SENSITIVITY IN GREEN WAVELENGTH REGION FUJI PHOTO FILM CO., LTD. (JP) 1990-11-13 US claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US claimed
EP-0278509-A2 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1988-08-17 EP claimed
EP-4737445-A1 NOVEL SATURATED HETEROCYCLE-SUBSTITUTED HETEROARYL-CARBONOHYDRAZONOYL DICYANIDE COMPOUND AND USE THEREOF Korea Institute of Science and Technology (KR) 2026-05-06 EP disclosed
US-20250002511-A1 AKT3 MODULATORS Georgiamune Inc. 2025-01-02 US disclosed
WO-2025005367-A1 NOVEL SATURATED HETEROCYCLE-SUBSTITUTED HETEROARYL-CARBONOHYDRAZONOYL DICYANIDE COMPOUND AND USE THEREOF 한국과학기술연구원 2025-01-02 WO disclosed
EP-4426279-A1 AKT3 MODULATORS Georgiamune Inc. (US) 2024-09-11 EP disclosed
EP-4426289-A1 AKT3 MODULATORS Georgiamune Inc. (US) 2024-09-11 EP disclosed
CN-118574610-A AKT3 modulators 乔治穆内公司 2024-08-30 CN disclosed
CN-118524833-A AKT3 modulators 乔治穆内公司 2024-08-20 CN disclosed
WO-2023081845-A1 AKT3 MODULATORS GEORGIAMUNE LLC (US) 2023-05-11 WO disclosed
US-4035190-A 2-ISOXAZOLIN-3-HETEROCYCLIC-SUBSTITUTED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-07-12 US disclosed
US-4028113-A Photographic supports and elements utilizing photobleachable O-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1977-06-07 US disclosed
US-4025347-A Fogged direct-positive silver halide emulsion containing a cyanine dye having an indole or indolenine nucleus substituted with a benzoyl or a phenylsulfonyl group MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-05-24 US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 US disclosed
US-3988156-A Photographic supports and elements utilizing photobleachable o-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-26 US disclosed
US-3988154-A Photographic supports and elements utilizing photobleachable omicron-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-26 US disclosed
US-3984248-A Photographic polymeric film supports containing photobleachable o-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-05 US disclosed
US-3955996-A Method for spectrally sensitizing photographic light-sensitive emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002511-A1 AKT3 MODULATORS AKT3, PIK3C2A, PIK3C2B CYP3A4 2616/4885NAMPT 2776/4885XDH 4186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.