Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19116362 | 0.84 | ALDH1A1 (0.43) | SMN1; SMN2HPGDALDH1A1OPRM1OPRD1 | |
| SCHEMBL18078097 | 0.83 | CACNA2D1 (0.46) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL15892775 | 0.82 | HPGD (0.40) | SMN1; SMN2TP53HPGDALDH1A1OPRM1 | |
| SCHEMBL15235369 | 0.81 | MTNR1A (0.53) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL12107529 | 0.80 | ALDH1A1 (0.39) | SMN1; SMN2TP53HPGDALDH1A1OPRM1 | |
| SCHEMBL18213763 | 0.79 | MGLL (0.42) | SMN1; SMN2TP53HPGDALDH1A1OPRM1 | |
| SCHEMBL16731691 | 0.79 | AKT1 (0.47) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL21648875 | 0.79 | PTGS1 (0.45) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL16120761 | 0.78 | PTGS1 (0.46) | HPGDALDH1A1OPRM1OPRD1OPRK1 | |
| SCHEMBL254148 | 0.78 | HSD17B10 (0.49) | SMN1; SMN2HPGDKMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579367-B2 | C-terminally tethered amino acids and their fibrinolytic therapeutic uses | CANADIAN BLOOD SERVICES (CA) | 2017-02-28 | — | — | US | disclosed |
| US-9579367-B2 | C-terminally tethered amino acids and their fibrinolytic therapeutic uses | CANADIAN BLOOD SERVICES (CA) | 2017-02-28 | — | — | US | disclosed |
| US-20140369992-A1 | C-Terminally Tethered Amino Acids and Their Fibrinolytic Therapeutic Uses | CANADIAN BLOOD SERVICES (CA) | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140369992-A1 | C-Terminally Tethered Amino Acids and Their Fibrinolytic Therapeutic Uses | HABP2, FGB, PROC | SMN1; SMN2 4220/4885TP53 2938/4885HPGD 2984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.