SCHEMBL163117

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL162581	0.85	ABCG2 (0.42)	ALDH1A1MAPTHPGDABCG2MEN1
	SCHEMBL166312	0.84	ALDH1A1 (0.47)	ALDH1A1MAPTHPGDMEN1KMT2A
	SCHEMBL164762	0.81	NPC1 (0.49)	ALDH1A1MAPTHPGDMEN1KMT2A
	SCHEMBL163764	0.81	KDM4E (0.50)	ALDH1A1MAPTHPGDMEN1KMT2A
	SCHEMBL163995	0.80	ABCG2 (0.38)	ALDH1A1ABCG2MEN1KMT2AATM
	SCHEMBL164557	0.78	LMNA (0.51)	ALDH1A1MAPTHPGDKMT2AGABRA1
	SCHEMBL162200	0.78	IMPDH2 (0.46)	ALDH1A1MAPTHPGDMEN1KMT2A
	SCHEMBL159959	0.77	ALDH1A1 (0.47)	ALDH1A1MAPTHPGDKMT2AKDM4E
	SCHEMBL162740	0.77	ALDH1A1 (0.49)	ALDH1A1MAPTHPGDMEN1KMT2A
	SCHEMBL163276	0.77	ALDH1A1 (0.51)	ALDH1A1MAPTHPGDCASP3GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.