SCHEMBL163995

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL162581	0.88	ABCG2 (0.42)	ABCG2GABRA1GABRG2GABRB3GABRA3
	SCHEMBL162792	0.83	TSHR (0.47)	MEN1KMT2ACA12CA1CA2
	SCHEMBL163117	0.80	ALDH1A1 (0.44)	ABCG2GABRA1GABRG2GABRB3GABRA3
	SCHEMBL539749	0.80	CES2 (0.48)	ABCG2GABRA1GABRG2GABRB3GABRA3
	SCHEMBL163819	0.79	CA12 (0.50)	MEN1KMT2ACA12CA1CA2
	SCHEMBL160305	0.79	CA12 (0.50)	MEN1KMT2ACA12CA1CA2
	SCHEMBL1415273	0.78	CES2 (0.55)	GABRA1GABRG2GABRB3GABRA3GABRA2
	SCHEMBL161660	0.77	LMNA (0.54)	MEN1KMT2ACA12CA1CA2
	SCHEMBL162474	0.77	MEN1 (0.46)	MEN1KMT2AHPGDS
	SCHEMBL163231	0.76	ALDH1A1 (0.49)	MEN1KMT2AATMALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.