Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.32 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632683 | 0.79 | KDM4E (0.48) | FAAHKDM4EALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL1633737 | 0.78 | KLKB1 (0.39) | CHRM3 | |
| SCHEMBL1631060 | 0.75 | L3MBTL1 (0.52) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL377607 | 0.74 | FAAH (0.37) | FAAHKDM4EALDH1A1NPSR1 | |
| SCHEMBL377467 | 0.73 | LMNA (0.44) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL377823 | 0.73 | LMNA (0.44) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1362390 | 0.72 | FAAH (0.41) | FAAHCHRM2CHRM1CHRM3DRD2 | |
| SCHEMBL21043975 | 0.72 | FAAH (0.63) | FAAHACHECXCR4DRD2DRD3 | |
| SCHEMBL30218448 | 0.72 | FAAH (0.63) | FAAHACHECXCR4DRD2DRD3 | |
| SCHEMBL377693 | 0.71 | RAB9A (0.40) | FAAHKDM4EALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932247-B2 | M3 muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2011-04-26 | — | — | US | disclosed |