Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16373176 | 0.85 | AKR1B10 (0.47) | GRIN2BHTR6HRH1PTGDR2PTGER2 | |
| SCHEMBL16373178 | 0.76 | AKR1B10 (0.49) | GRIN2BBAZ2BHTR6HRH1PTGDR2 | |
| SCHEMBL4125506 | 0.75 | HTR6 (0.54) | GRIN2BBAZ2BHTR6HRH1PTGDR2 | |
| SCHEMBL14067856 | 0.75 | HTR6 (0.69) | GRIN2BBAZ2BHTR6HRH1PTGDR2 | |
| SCHEMBL16373179 | 0.74 | AKR1B10 (0.61) | HTR6HRH1PTGDR2 | |
| SCHEMBL17782078 | 0.74 | SIGMAR1 (0.58) | GRIN2B | |
| SCHEMBL16373181 | 0.74 | MAOA (0.63) | HTR6HRH1BCHE | |
| SCHEMBL16373180 | 0.72 | AKR1B10 (0.44) | HTR6HRH1PTGDR2PTGER2PTGDR | |
| SCHEMBL14067656 | 0.70 | PTGDR2 (0.55) | GRIN2BBAZ2BPTGDR2PTGER2PTGDR | |
| SCHEMBL4137410 | 0.68 | HRH1 (0.58) | HTR6HRH1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014207241-A1 | NEW Na-SUBSTITUTED CARBOLINE COMPOUNDS USABLE FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | ALZPROTECT (FR) | 2014-12-31 | — | — | WO | disclosed |