Benzil

Benzil

SCHEMBL1634137

O=C(C(=O)c1ccccc1)c1ccccc1.[GeH4]

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 12/20 0.93
CES1 P23141 12/20 0.93
TSHR P16473 2/20 0.61
DAO P14920 1/20 0.61
NAPRT Q6XQN6 1/20 0.61
ALDH1A1 P00352 1/20 0.61
RAB9A P51151 1/20 0.58
CYP3A4 P08684 2/20 0.55
MAPT P10636 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
CA2 P00918 2/20 0.55
CA4 P22748 2/20 0.55
POLB P06746 1/20 0.55
PARP1 P09874 1/20 0.55
CYP2C19 P33261 1/20 0.55
RECQL P46063 1/20 0.55
BLM P54132 1/20 0.55
PMP22 Q01453 1/20 0.55
HSD17B10 Q99714 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzil SCHEMBL2156589 0.97 CES2 (1.00) CES2CES1TSHRDAONAPRT
Benzil SCHEMBL28475956 0.97 CES2 (1.00) CES2CES1TSHRDAONAPRT
Benzil SCHEMBL66 0.97 CES2 (1.00) CES2CES1TSHRDAONAPRT
Benzil SCHEMBL9517636 0.97 CES2 (1.00) CES2CES1TSHRDAONAPRT
Benzil SCHEMBL7142843 0.97 CES2 (1.00) CES2CES1TSHRDAONAPRT
Benzil SCHEMBL1311689 0.93 CES2 (0.93) CES2CES1TSHRDAONAPRT
Benzil SCHEMBL4957522 0.93 CES2 (1.00) CES2CES1TSHRDAONAPRT
Benzil SCHEMBL16390243 0.93 CES2 (0.93) CES2CES1TSHRDAONAPRT
Benzil SCHEMBL9799726 0.93 CES2 (0.93) CES2CES1TSHRDAONAPRT
SCHEMBL1195835 0.93 CES2 (1.00) CES2CES1TSHRDAONAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240052079-A1 ANTIBACTERIAL ESTER-FREE MONOMERS FOR DENTAL ADHESIVES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-02-15 US claimed
EP-3911687-B1 LIMONENE-BASED (METH)ACRYLATES FOR USE IN 3D PRINTING BASF SE (DE) 2023-11-01 EP claimed
WO-2022178440-A1 ANTIBACTERIAL ESTER-FREE MONOMERS FOR DENTAL ADHESIVES OREGON HEALTH & SCIENCE UNIVERSITY (US) 2022-08-25 WO claimed
US-20220064350-A1 LIMONENE-BASED (METH)ACRYLATES FOR USE IN 3D PRINTING BASF SE (DE) 2022-03-03 US claimed
EP-3911691-A1 HYDROXYURETHANE (METH)ACRYLATE PREPOLYMERS FOR USE IN 3D PRINTING BASF SE (DE) 2021-11-24 EP claimed
EP-3911687-A1 LIMONENE-BASED (METH)ACRYLATES FOR USE IN 3D PRINTING BASF SE (DE) 2021-11-24 EP claimed
WO-2020148189-A1 LIMONENE-BASED (METH)ACRYLATES FOR USE IN 3D PRINTING BASF SE (DE) 2020-07-23 WO claimed
WO-2020148190-A1 HYDROXYURETHANE (METH)ACRYLATE PREPOLYMERS FOR USE IN 3D PRINTING BASF SE (DE) 2020-07-23 WO claimed
EP-3680263-A1 LIMONENE-BASED (METH)ACRYLATES FOR USE IN 3D PRINTING BASF SE (DE) 2020-07-15 EP claimed
EP-3680274-A1 HYDROXYURETHANE (METH)ACRYLATE PREPOLYMERS FOR USE IN 3D PRINTING BASF SE (DE) 2020-07-15 EP claimed
US-10689329-B2 Tert-amine core-bearing acyrlamides and adhesive formulations OREGON HEALTH & SCIENCE UNIVERSITY 2020-06-23 US claimed
US-20190292136-A1 Tert-AMINE CORE-BEARING ACYRLAMIDES AND ADHESIVE FORMULATIONS OREGON HEALTH & SCIENCE UNIVERSITY 2019-09-26 US claimed
US-20170156993-A1 DENTAL MATERIALS WITH DEBONDING-ON-DEMAND PROPERTIES TECHNISCHE UNIVERSITÄT WIEN (AT) 2017-06-08 US claimed
CN-105246562-A Golf ball with visible light-cured coating and method NIKE INNOVATE CV 2016-01-13 CN claimed
EP-4724420-A1 SYNTHESIS OF FUNCTIONAL AND CLINICALLY PRACTICAL ESTER-FREE VINYL MONOMERS FOR APPLICATIONS IN DENTISTRY The Governing Council of the University of Toronto (CA) 2026-04-15 EP disclosed
EP-4155700-B1 THERMO-FLUORESCENT OPTICAL FIBRE, METHOD FOR MANUFACTURING SAME AND USES THEREOF COMMISSARIAT ENERGIE ATOMIQUE (FR) 2026-03-25 EP disclosed
US-12514791-B2 Aesthetic dental filling material having high curing depth IVOCLAR VIVADENT AG (LI) 2026-01-06 US disclosed
US-7932304-B2 Polymer-coated glass filler for use in dental materials IVOCLAR VIVADENT AG (LI) 2011-04-26 US disclosed
US-20100240796-A1 UNIVERSAL DENTAL ADHESION-PROMOTER COMPOSITION IVOCLAR VIVADENT AG (LI) 2010-09-23 US disclosed
US-20090239971-A1 POLYMER-COATED GLASS FILLER FOR USE IN DENTAL MATERIALS IVOCLAR VIVADENT AG (LI) 2009-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240052079-A1 ANTIBACTERIAL ESTER-FREE MONOMERS FOR DENTAL ADHESIVES CDH1, ICAM1, CAD CES2 310/4885CES1 1210/4885TSHR 4167/4885
US-20190292136-A1 Tert-AMINE CORE-BEARING ACYRLAMIDES AND ADHESIVE FORMULATIONS TERT, TAS2R42, TERF2IP CES2 2094/4885CES1 4069/4885TSHR 505/4885
US-20220064350-A1 LIMONENE-BASED (METH)ACRYLATES FOR USE IN 3D PRINTING LIMK1, LIMA1, LIMK2 CES2 1792/4885CES1 3059/4885TSHR 3518/4885
US-20100240796-A1 UNIVERSAL DENTAL ADHESION-PROMOTER COMPOSITION CDH1, CAD, CD44 CES2 2155/4885CES1 3235/4885TSHR 4027/4885
US-20170156993-A1 DENTAL MATERIALS WITH DEBONDING-ON-DEMAND PROPERTIES DCLRE1A, RAD51, TERB1 CES2 1951/4885CES1 3974/4885TSHR 3799/4885
US-10689329-B2 Tert-amine core-bearing acyrlamides and adhesive formulations TERT, TAS2R42, TERF2IP CES2 2094/4885CES1 4069/4885TSHR 505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.