Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | KLF10 | Q13118 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16347642 | 0.92 | SLC6A9 (0.47) | SLC6A4CYP1A2CYP3A4SLC6A2CYP2D6 | |
| SCHEMBL4936018 | 0.84 | CYP1A2 (0.43) | SLC6A4CYP1A2CYP3A4SLC6A2CYP2D6 | |
| SCHEMBL5403848 | 0.81 | SLC6A2 (0.50) | SLC6A4CYP1A2CYP3A4SLC6A2CYP2D6 | |
| SCHEMBL5029640 | 0.81 | SLC6A2 (0.50) | SLC6A4CYP1A2CYP3A4SLC6A2CYP2D6 | |
| SCHEMBL8011874 | 0.76 | NOS2 (0.47) | SLC6A4SLC6A2CYP2D6TSHRKCNH2 | |
| SCHEMBL11357411 | 0.76 | ALDH1A1 (0.41) | SLC6A4SLC6A2KCNH2KMT2AALDH1A1 | |
| SCHEMBL7310728 | 0.75 | SLC6A9 (0.49) | SLC6A4LMNASLC6A9NPSR1HTR1A | |
| SCHEMBL4740090 | 0.75 | UTS2R (0.42) | SLC6A4SLC6A9HTR1APPARGPPARA | |
| SCHEMBL10155 | 0.74 | TRPM8 (0.42) | SLC6A2TP53HPGD | |
| SCHEMBL2526 | 0.74 | HTT (0.44) | SLC6A4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004470-A1 | Synthesis of Atomoxetine Hydrochloride | DR. REDDY'S LABORATORIES LIMITED (IN) | 2008-01-03 | — | — | US | disclosed |
| EP-1794112-A1 | SYNTHESIS OF ATOMOXETINE HYDROCHLORIDE | Dr. Reddy's Laboratories Ltd. (IN) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006037055-A1 | SYNTHESIS OF ATOMOXETINE HYDROCHLORIDE | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-06 | — | — | WO | disclosed |
| WO-2006009884-A1 | 3-ARYLOXY-3-ARYLPROPYLAMINE SYNTHESIS | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004470-A1 | Synthesis of Atomoxetine Hydrochloride | SLC6A2, SLC6A4, SLC6A3 | SLC6A4 2/4885CYP1A2 55/4885CYP3A4 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.