Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310728 | 0.95 | SLC6A9 (0.49) | SLC6A9PPARGPPARAHTR1ANPSR1 | |
| SCHEMBL4936018 | 0.87 | CYP1A2 (0.43) | SLC6A9PPARGPPARAHTR1ANPSR1 | |
| SCHEMBL7318669 | 0.82 | SLC6A4 (0.49) | SLC6A9PPARGPPARAHTR1ASLC6A4 | |
| SCHEMBL7409524 | 0.82 | SLC6A4 (0.49) | SLC6A9PPARGPPARAHTR1ANPSR1 | |
| SCHEMBL143604 | 0.80 | SLC6A9 (0.45) | SLC6A9PPARGPPARAHTR1ASLC6A4 | |
| SCHEMBL7306077 | 0.79 | SLC6A4 (0.59) | SLC6A9ALDH1A1HPGDSLC6A4LMNA | |
| SCHEMBL5533205 | 0.78 | SLC6A9 (0.46) | SLC6A9HTR1ANPSR1SLC6A4 | |
| SCHEMBL16347642 | 0.77 | SLC6A9 (0.47) | SLC6A9PPARGPPARAHTR1ANPSR1 | |
| SCHEMBL7310188 | 0.77 | LMNA (0.47) | SLC6A4LMNA | |
| SCHEMBL7312423 | 0.76 | SLC6A9 (0.46) | SLC6A9PPARGPPARAHTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008026227-A2 | A PROCESS FOR THE PREPARATION OF ATOMOXETINE HYDROCHLORIDE | MATRIX LABORATORIES LTD (IN) | 2008-03-06 | — | — | WO | disclosed |