Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348319 | 0.94 | ACSS2 (0.40) | NPC1RAB9ASMN1; SMN2POLBACSS2 | |
| SCHEMBL16348359 | 0.90 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2POLBACSS2 | |
| SCHEMBL16348381 | 0.85 | RAB9A (0.39) | NPC1RAB9ASMN1; SMN2POLBACSS2 | |
| SCHEMBL16348327 | 0.76 | PPARA (0.46) | NPC1RAB9ASMN1; SMN2POLBCYP1A2 | |
| SCHEMBL16348309 | 0.73 | PPARA (0.52) | NPC1RAB9ASMN1; SMN2POLBCYP1A2 | |
| SCHEMBL16348312 | 0.72 | PPARA (0.43) | NPC1RAB9ASMN1; SMN2POLBCYP1A2 | |
| SCHEMBL16348326 | 0.72 | PPARG (0.41) | SMN1; SMN2JMJD6 | |
| SCHEMBL16348367 | 0.69 | JMJD6 (0.39) | NPC1RAB9ASMN1; SMN2POLBCYP1A2 | |
| SCHEMBL13523181 | 0.68 | IDO1 (0.44) | NPC1RAB9ASMN1; SMN2POLBCYP1A2 | |
| SCHEMBL16348313 | 0.68 | PPARG (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |