Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348319 | 0.91 | ACSS2 (0.40) | RAB9ANPC1SMN1; SMN2POLBACSS2 | |
| SCHEMBL16348328 | 0.85 | NPC1 (0.41) | RAB9ANPC1SMN1; SMN2POLBACSS2 | |
| SCHEMBL16348359 | 0.85 | NPC1 (0.39) | RAB9ANPC1SMN1; SMN2POLBACSS2 | |
| SCHEMBL16348309 | 0.74 | PPARA (0.52) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL16348312 | 0.69 | PPARA (0.43) | RAB9ANPC1SMN1; SMN2POLBCYP1A2 | |
| SCHEMBL16348360 | 0.67 | JMJD6 (0.42) | RAB9ANPC1SMN1; SMN2POLBTSHR | |
| SCHEMBL16350102 | 0.67 | PPARG (0.46) | RAB9ANPC1SMN1; SMN2TSHRRECQL | |
| SCHEMBL16348318 | 0.66 | PTGER1 (0.39) | RAB9ANPC1SMN1; SMN2CYP2C9MAPT | |
| SCHEMBL16348367 | 0.66 | JMJD6 (0.39) | RAB9ANPC1SMN1; SMN2POLBTSHR | |
| SCHEMBL16348369 | 0.65 | PPARA (0.48) | CYP1A2CYP2D6CYP2C19KMT2APTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |