Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348328 | 0.90 | NPC1 (0.41) | NPC1POLBRAB9ASMN1; SMN2JMJD6 | |
| SCHEMBL16348381 | 0.85 | RAB9A (0.39) | NPC1POLBRAB9ASMN1; SMN2JMJD6 | |
| SCHEMBL16348319 | 0.84 | ACSS2 (0.40) | NPC1POLBRAB9ASMN1; SMN2JMJD6 | |
| SCHEMBL16348326 | 0.75 | PPARG (0.41) | SMN1; SMN2JMJD6HTT | |
| SCHEMBL16348367 | 0.72 | JMJD6 (0.39) | NPC1POLBRAB9ASMN1; SMN2JMJD6 | |
| SCHEMBL16348327 | 0.72 | PPARA (0.46) | NPC1POLBRAB9ASMN1; SMN2JMJD6 | |
| SCHEMBL16348360 | 0.72 | JMJD6 (0.42) | NPC1POLBRAB9ASMN1; SMN2JMJD6 | |
| SCHEMBL16348309 | 0.69 | PPARA (0.52) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16348312 | 0.68 | PPARA (0.43) | NPC1POLBRAB9ASMN1; SMN2PPARA | |
| SCHEMBL13523181 | 0.66 | IDO1 (0.44) | NPC1POLBRAB9ASMN1; SMN2JMJD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |